Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
cspE-3Function of homologous gene experimentally demonstrated in an other organism; molecular chaperone. (69 aa)    
Predicted Functional Partners:
deaD
ATP-dependent RNA helicase, cold shock protein A; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
 0.716
rnr-2
Cold-shock RNAse R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
   
 
 0.473
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
   
   0.472
rpsQ
30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
   
 
 0.466
htpG
Chaperone protein htpG; Molecular chaperone. Has ATPase activity.
   
 
 0.464
cspE-2
RNA chaperone, transcription antiterminator, affects expression of rpoS and uspA; Function of homologous gene experimentally demonstrated in an other organism; molecular chaperone.
 
    
0.454
gabD
Succinate-semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.453
rplW
50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.
   
   0.439
rpsS
30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
 
 0.434
rpmC
50S ribosomal subunit protein L29; Function of homologous gene experimentally demonstrated in an other organism; structural protein; Belongs to the universal ribosomal protein uL29 family.
   
   0.420
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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