STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVI78097.1SAM-dependent methyltransferase. (400 aa)    
Predicted Functional Partners:
xerC
Site-specific tyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.
       0.696
CVI85894.1
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
    
  0.670
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
    
  0.667
CVI78100.1
Hypothetical protein.
       0.665
folD
Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
  0.633
CVI85530.1
Bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
  
 
  0.623
gcvT
Glycine cleavage system aminomethyltransferase T; The glycine cleavage system catalyzes the degradation of glycine.
    
  0.621
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
       0.580
CVI78095.1
Cobalamin synthesis protein, P47K.
       0.507
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
  0.479
Your Current Organism:
Caballeronia humi
NCBI taxonomy Id: 326474
Other names: Burkholderia humi, Burkholderia humi Vandamme et al. 2013, Burkholderia sp. LMG 22934, Burkholderia sp. LMG 22935, Burkholderia sp. R-23322, Burkholderia sp. R-23323, Burkholderia sp. R-23328, Burkholderia sp. R-23370, C. humi, CCUG 63059, Caballeronia humi (Vandamme et al. 2013) Dobritsa and Samadpour 2016, LMG 22934, LMG:22934, Paraburkholderia humi, Paraburkholderia humi (Vandamme et al. 2013) Sawana et al. 2015, strain RA1-5
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.