STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CVI80518.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (413 aa)    
Predicted Functional Partners:
CVI75986.1
Ribonucleotide reductase system; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.999
CVI80531.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
cmk
Cytidylate kinase.
    
 0.897
CVI82435.1
Pyochelin synthetase.
 
 0.894
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.867
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.864
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.851
CVI82432.1
Beta-ketoacyl synthase.
  
 
 0.838
CVI85077.1
Non-ribosomal peptide synthetase.
  
 0.833
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.828
Your Current Organism:
Caballeronia humi
NCBI taxonomy Id: 326474
Other names: Burkholderia humi, Burkholderia humi Vandamme et al. 2013, Burkholderia sp. LMG 22934, Burkholderia sp. LMG 22935, Burkholderia sp. R-23322, Burkholderia sp. R-23323, Burkholderia sp. R-23328, Burkholderia sp. R-23370, C. humi, CCUG 63059, Caballeronia humi (Vandamme et al. 2013) Dobritsa and Samadpour 2016, LMG 22934, LMG:22934, Paraburkholderia humi, Paraburkholderia humi (Vandamme et al. 2013) Sawana et al. 2015, strain RA1-5
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