STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGM70994.1uroporphyrinogen-III methyltransferase; Belongs to the precorrin methyltransferase family. (277 aa)    
Predicted Functional Partners:
EGM69355.1
Siroheme synthase / Precorrin-2 oxidase / Sirohydrochlorin ferrochelatase.
 
 0.998
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.993
EGM71755.1
Uroporphyrinogen-3 synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.929
hemE
Uroporphyrinogen III decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.927
EGM68051.1
uroporphyrinogen-III methyltransferase.
  
  
 
0.923
EGM71754.1
Putative HemX protein.
     
 0.913
cysI
Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
 
 0.898
EGM69876.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.884
EGM68591.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.875
cysD
Sulfate adenylyltransferase subunit 2.
  
  
 0.830
Your Current Organism:
Shewanella sp. HN41
NCBI taxonomy Id: 327275
Other names: S. sp. HN-41, Shewanella sp. HN-41
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.