STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (331 aa)    
Predicted Functional Partners:
TAH18
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
    
 0.983
AU210_000616
Uncharacterized protein.
    
 
 0.950
AU210_011324
Glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily.
    
 
 0.945
AU210_001699
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.873
AU210_004376
Uncharacterized protein; Belongs to the BolA/IbaG family.
    
 
 0.802
AU210_014919
Cytochrome b5 heme-binding domain-containing protein.
    
 0.774
AU210_014244
Uncharacterized protein; Belongs to the glycosyl hydrolase 43 family.
    
 0.774
AU210_012170
Uncharacterized protein.
    
 0.774
AU210_009252
NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450.
    
 0.774
AU210_009305
FAD-binding FR-type domain-containing protein.
    
 0.774
Your Current Organism:
Fusarium oxysporum f. sp. radiciscucumerinum
NCBI taxonomy Id: 327505
Other names: F. oxysporum f. sp. radicis-cucumerinum, Fusarium oxysporum f. sp. radicis-cucumerinum
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.