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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRSS12Serine protease 12. (742 aa)    
Predicted Functional Partners:
MET
Hepatocyte growth factor receptor.
    
 0.845
ENSMVIP00005020836
annotation not available
    
 0.845
PTK7
Inactive tyrosine-protein kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.752
WDR90
WD repeat-containing protein 90.
    
 0.695
SPINT1
Kunitz-type protease inhibitor 1.
    
 0.641
HRG
Histidine rich glycoprotein.
    
  0.613
F2RL3
Proteinase-activated receptor 4; Belongs to the G-protein coupled receptor 1 family.
    
  0.608
F3
Tissue factor.
    
 0.607
TFPI
Tissue factor pathway inhibitor.
    
 0.602
ENSMVIP00005020988
annotation not available
    
 0.602
Your Current Organism:
Manacus vitellinus
NCBI taxonomy Id: 328815
Other names: M. vitellinus, golden-collared manakin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.