STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERPUD2Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein. (453 aa)    
Predicted Functional Partners:
AMFR
E3 ubiquitin-protein ligase AMFR.
    
 
 0.722
ATF4
Cyclic AMP-dependent transcription factor ATF-4.
   
 
 0.676
FAM8A1
Protein FAM8A1.
    
 
 0.568
RNF145
RING finger protein 145.
    
 
 0.449
RNF185
E3 ubiquitin-protein ligase RNF185.
      
 0.435
CHFR
Checkpoint with forkhead and ring finger domains.
    
 
 0.431
RNF139
E3 ubiquitin-protein ligase RNF139.
    
 
 0.431
ENSMVIP00005026978
annotation not available
    
 
 0.431
SEL1L
Protein sel-1 1.
    
 
 0.413
Your Current Organism:
Manacus vitellinus
NCBI taxonomy Id: 328815
Other names: M. vitellinus, golden-collared manakin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.