STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SOS1Son of sevenless 1. (1265 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
   
 0.998
EGFR
Receptor protein-tyrosine kinase.
    
 0.985
N305_00927
Tyrosine-protein phosphatase non-receptor type 11.
    
 0.982
PTPN11
Tyrosine-protein phosphatase non-receptor type 11.
    
 0.982
HRAS
GTPase HRas.
   
 0.981
NRAS
GTPase NRas.
   
 0.980
MRAS
Ras-related protein M-Ras.
    
 0.963
KRAS
KRAS proto-oncogene, GTPase.
   
 0.963
RRAS2
Ras-related protein R-Ras2.
    
 0.959
FGFR3
Fibroblast growth factor receptor 3.
    
 0.958
Your Current Organism:
Manacus vitellinus
NCBI taxonomy Id: 328815
Other names: M. vitellinus, golden-collared manakin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.