STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2D2S4HECT domain-containing protein. (1866 aa)    
Predicted Functional Partners:
A0A1Y2CCL6
U-box domain-containing protein.
   
 0.991
A0A1Y2CMK7
E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
   
 0.989
A0A1Y2BRV5
E2_bind domain-containing protein.
    
 0.987
A0A1Y2C126
Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family.
   
 0.987
A0A1Y2BPS3
Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 and ATG8 for its conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Autophagy is essential for maintenance of amino acid levels and protein synthesis under nitrogen starvation. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy wh [...]
    
 0.979
A0A1Y2CNK9
Uncharacterized protein.
   
  0.979
A0A1Y2CRB9
C2 domain-containing protein.
   
  
 0.970
A0A1Y2B3L9
ESCRT-II complex, vps25 subunit.
   
 0.949
A0A1Y2B599
UBC-like protein.
   
 0.949
A0A1Y2B9H8
Ubiquitin-conjugating enzyme E2; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.949
Your Current Organism:
Rhizoclosmatium globosum
NCBI taxonomy Id: 329046
Other names: R. globosum, Rhizoclosmatium sp. JEL06
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.