STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SCX06068.1Isochorismate synthase. (360 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.989
SCX06201.1
Anthranilate synthase component 1.
  
  
 0.976
SCX06195.1
Anthranilate synthase component 2.
  
 
  0.972
SCX12500.1
3-deoxy-D-arabinoheptulosonate-7-phosphate synthase.
  
 
 0.964
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.950
SCX01917.1
Aspartate aminotransferase.
    
  0.911
SCX14341.1
Aspartate aminotransferase.
    
  0.911
SCX06062.1
Uncharacterized domain 1-containing protein.
 
  
 0.908
menB
1,4-Dihydroxy-2-naphthoyl-CoA synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.789
SCX06075.1
Bacillithiol biosynthesis deacetylase BshB1.
       0.780
Your Current Organism:
Flavobacterium saliperosum
NCBI taxonomy Id: 329186
Other names: AS 1.3801, CGMCC 1.3801, F. saliperosum, Flavobacterium saliperosum Wang et al. 2006 emend. Dong et al. 2013, Flavobacterium saliperosum Wang et al. 2006 emend. Hahnke et al. 2016, JCM 13331, strain S13
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