STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nthEndonuclease-3; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (224 aa)    
Predicted Functional Partners:
SCX03496.1
Exodeoxyribonuclease-3.
 
 0.972
SCX18424.1
Endonuclease-3.
  
  
 
0.932
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.662
SCX14735.1
Peroxiredoxin Q/BCP.
       0.605
ung
Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
 
  
 0.553
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
    
 
 0.442
SCX18618.1
ABC-type Fe3+-hydroxamate transport system, substrate-binding protein.
 
      0.426
SCX03488.1
Chemotaxis protein MotB.
    
   0.416
SCX18280.1
Chemotaxis protein MotB.
    
   0.416
Your Current Organism:
Flavobacterium saliperosum
NCBI taxonomy Id: 329186
Other names: AS 1.3801, CGMCC 1.3801, F. saliperosum, Flavobacterium saliperosum Wang et al. 2006 emend. Dong et al. 2013, Flavobacterium saliperosum Wang et al. 2006 emend. Hahnke et al. 2016, JCM 13331, strain S13
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