B0A54_17782 protein (Friedmanniomyces endolithicus)

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Predicted Interactions

gene neighborhood

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Score

B0A54_17782

Uncharacterized protein. (283 aa)

Predicted Functional Partners:

B0A54_10341

0.569

B0A54_00889

0.569

B0A54_08316

0.565

B0A54_03805

0.565

B0A54_07536

0.564

B0A54_05454

0.564

B0A54_04884

0.564

B0A54_01865

0.564

B0A54_04464

0.551

B0A54_03874

0.551

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_00889	B0A54_03805	A0A4U0VIC0	A0A4V5N9I8	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.997
B0A54_00889	B0A54_08316	A0A4U0VIC0	A0A4V5N7H9	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.997
B0A54_00889	B0A54_17782	A0A4U0VIC0	A0A4U0TQN8	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Uncharacterized protein.	0.569
B0A54_01865	B0A54_17782	A0A4U0VF04	A0A4U0TQN8	CRAL-TRIO domain-containing protein.	Uncharacterized protein.	0.564
B0A54_03805	B0A54_00889	A0A4V5N9I8	A0A4U0VIC0	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.997
B0A54_03805	B0A54_10341	A0A4V5N9I8	A0A4U0UTX3	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.997
B0A54_03805	B0A54_17782	A0A4V5N9I8	A0A4U0TQN8	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Uncharacterized protein.	0.565
B0A54_03874	B0A54_04464	A0A4U0VD54	A0A4U0V911	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.843
B0A54_03874	B0A54_17782	A0A4U0VD54	A0A4U0TQN8	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.551
B0A54_04464	B0A54_03874	A0A4U0V911	A0A4U0VD54	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	0.843
B0A54_04464	B0A54_17782	A0A4U0V911	A0A4U0TQN8	DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.	Uncharacterized protein.	0.551
B0A54_04884	B0A54_17782	A0A4U0V5T8	A0A4U0TQN8	CRAL-TRIO domain-containing protein.	Uncharacterized protein.	0.564
B0A54_05454	B0A54_17782	A0A4U0V4P3	A0A4U0TQN8	CRAL-TRIO domain-containing protein.	Uncharacterized protein.	0.564
B0A54_07536	B0A54_17782	A0A4U0V2U1	A0A4U0TQN8	CRAL-TRIO domain-containing protein.	Uncharacterized protein.	0.564
B0A54_08316	B0A54_00889	A0A4V5N7H9	A0A4U0VIC0	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.997
B0A54_08316	B0A54_10341	A0A4V5N7H9	A0A4U0UTX3	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	0.997
B0A54_08316	B0A54_17782	A0A4V5N7H9	A0A4U0TQN8	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	Uncharacterized protein.	0.565
B0A54_10341	B0A54_03805	A0A4U0UTX3	A0A4V5N9I8	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.997
B0A54_10341	B0A54_08316	A0A4U0UTX3	A0A4V5N7H9	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Histone chaperone; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.	0.997
B0A54_10341	B0A54_17782	A0A4U0UTX3	A0A4U0TQN8	Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family.	Uncharacterized protein.	0.569

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.706

expected number of edges:

15

PPI enrichment p-value:

0.000868

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006753

Nucleoside phosphate metabolic process

6 of 153

1.46

1.56

7.44e-05

GO:0009117

Nucleotide metabolic process

5 of 148

1.39

1.33

0.00031

GO:0019637

Organophosphate metabolic process

7 of 328

1.19

1.22

9.41e-05

GO:0009259

Ribonucleotide metabolic process

4 of 110

1.42

1.07

0.0031

GO:0000290

Deadenylation-dependent decapping of nuclear-transcribed mRNA

2 of 8

2.26

1.06

0.0106

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0052857

NADPHX epimerase activity

2 of 2

2.86

1.02

0.0146

GO:0052856

NADHX epimerase activity

2 of 2

2.86

1.02

0.0146

GO:0004551

Nucleotide diphosphatase activity

2 of 5

2.46

0.97

0.0170

GO:0047429

Nucleoside-triphosphate diphosphatase activity

2 of 6

2.39

0.96

0.0170

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9541

Mixed, incl. AMP metabolic process, and GMP biosynthesis

3 of 16

2.14

1.71

0.00049

CL:5292

mRNA decay by 5 to 3 exoribonuclease, and U6 snRNP

3 of 17

2.11

1.7

0.00049

CL:9538

Metabolism of nucleotides, and Purine nucleoside metabolic process

4 of 45

1.81

1.65

0.00033

CL:9534

Mixed, incl. Metabolism of nucleotides, and Nicotinate and nicotinamide metabolism

5 of 111

1.52

1.44

0.00033

CL:5315

Stress granule assembly, and Deadenylation-independent decapping of nuclear-transcribed mRNA

2 of 5

2.46

1.28

0.0044

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00240

Pyrimidine metabolism

3 of 58

1.58

0.95

0.0099

map03018

RNA degradation

3 of 85

1.41

0.83

0.0148

map00230

Purine metabolism

3 of 88

1.4

0.82

0.0148

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000932

P-body

3 of 17

2.11

1.41

0.0020

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0665

Pyrimidine biosynthesis

2 of 3

2.69

1.33

0.0038

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