B0A54_17600 protein (Friedmanniomyces endolithicus)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Gene Fusion

Cooccurrence

Coexpression

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Score

B0A54_17600

Amidase domain-containing protein. (571 aa)

Predicted Functional Partners:

B0A54_16078

0.895

B0A54_07063

0.895

B0A54_14255

0.704

B0A54_00389

0.704

B0A54_16490

0.625

B0A54_12774

0.625

B0A54_16165

0.613

B0A54_16242

0.613

B0A54_15721

0.613

B0A54_03576

0.613

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_00389	B0A54_03576	A0A4U0VK83	A0A4U0VAE5	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.782
B0A54_00389	B0A54_07063	A0A4U0VK83	A0A4U0V2T8	AA_TRNA_LIGASE_II domain-containing protein.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.996
B0A54_00389	B0A54_12774	A0A4U0VK83	A0A4U0UNP7	AA_TRNA_LIGASE_II domain-containing protein.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.831
B0A54_00389	B0A54_15721	A0A4U0VK83	A0A4U0U8T5	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.747
B0A54_00389	B0A54_16078	A0A4U0VK83	A0A4U0U165	AA_TRNA_LIGASE_II domain-containing protein.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.995
B0A54_00389	B0A54_16165	A0A4U0VK83	A0A4U0TXS1	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.747
B0A54_00389	B0A54_16242	A0A4U0VK83	A0A4U0U101	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.782
B0A54_00389	B0A54_16490	A0A4U0VK83	A0A4U0U1C7	AA_TRNA_LIGASE_II domain-containing protein.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.831
B0A54_00389	B0A54_17600	A0A4U0VK83	A0A4U0TSF1	AA_TRNA_LIGASE_II domain-containing protein.	Amidase domain-containing protein.	0.704
B0A54_03576	B0A54_00389	A0A4U0VAE5	A0A4U0VK83	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	AA_TRNA_LIGASE_II domain-containing protein.	0.782
B0A54_03576	B0A54_07063	A0A4U0VAE5	A0A4U0V2T8	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.958
B0A54_03576	B0A54_12774	A0A4U0VAE5	A0A4U0UNP7	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.463
B0A54_03576	B0A54_14255	A0A4U0VAE5	A0A4U0UEZ5	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	AA_TRNA_LIGASE_II domain-containing protein.	0.782
B0A54_03576	B0A54_16078	A0A4U0VAE5	A0A4U0U165	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.958
B0A54_03576	B0A54_16165	A0A4U0VAE5	A0A4U0TXS1	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.984
B0A54_03576	B0A54_16490	A0A4U0VAE5	A0A4U0U1C7	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.463
B0A54_03576	B0A54_17600	A0A4U0VAE5	A0A4U0TSF1	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	Amidase domain-containing protein.	0.613
B0A54_07063	B0A54_00389	A0A4U0V2T8	A0A4U0VK83	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	AA_TRNA_LIGASE_II domain-containing protein.	0.996
B0A54_07063	B0A54_03576	A0A4U0V2T8	A0A4U0VAE5	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	Uncharacterized protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.958
B0A54_07063	B0A54_12774	A0A4U0V2T8	A0A4U0UNP7	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	tRNA-synt_1c domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.910

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

36

average node degree:

6.55

avg. local clustering coefficient:

0.631

expected number of edges:

21

PPI enrichment p-value:

0.00195

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019439

Aromatic compound catabolic process

8 of 44

1.63

2.89

2.49e-09

GO:0009056

Catabolic process

9 of 136

1.19

1.57

1.11e-07

GO:0044270

Cellular nitrogen compound catabolic process

3 of 29

1.38

0.75

0.0230

GO:0046700

Heterocycle catabolic process

3 of 32

1.34

0.7

0.0278

GO:0044281

Small molecule metabolic process

11 of 523

0.69

0.65

6.89e-06

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0051537

2 iron, 2 sulfur cluster binding

4 of 9

2.02

2.05

7.01e-05

GO:0071949

FAD binding

3 of 6

2.07

1.57

0.00089

GO:0016491

Oxidoreductase activity

8 of 247

0.88

0.78

0.00029

GO:0043167

Ion binding

9 of 681

0.49

0.33

0.0247

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2554

Aromatic compound catabolic process

8 of 16

2.07

4.97

1.35e-12

CL:2556

CO dehydrogenase flavoprotein, C-terminal, and Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

6 of 7

2.3

4.57

3.52e-10

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00230

Purine metabolism

4 of 90

1.02

0.59

0.0257

map01120

Microbial metabolism in diverse environments

6 of 236

0.78

0.48

0.0225

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01799

[2Fe-2S] binding domain

3 of 3

2.37

1.77

0.00047

PF00941

FAD binding domain in molybdopterin dehydrogenase

3 of 3

2.37

1.77

0.00047

PF00111

2Fe-2S iron-sulfur cluster binding domain

3 of 5

2.15

1.72

0.00047

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036683

CO dehydrogenase flavoprotein, C-terminal domain superfamily

4 of 4

2.37

2.53

1.44e-05

IPR005107

CO dehydrogenase flavoprotein, C-terminal

4 of 4

2.37

2.53

1.44e-05

IPR036884

[2Fe-2S]-binding domain superfamily

3 of 3

2.37

1.79

0.00044

IPR002888

[2Fe-2S]-binding

3 of 3

2.37

1.79

0.00044

IPR002346

Molybdopterin dehydrogenase, FAD-binding

3 of 3

2.37

1.79

0.00044

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01092

CO dehydrogenase flavoprotein C-terminal domain

3 of 3

2.37

2.07

0.00012

SM01008

Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain

2 of 5

1.97

0.92

0.0177

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