B0A54_17066 protein (Friedmanniomyces endolithicus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

B0A54_17066

Uncharacterized protein. (278 aa)

Predicted Functional Partners:

B0A54_10136

0.684

B0A54_05127

0.684

B0A54_12613

0.677

B0A54_07042

0.676

B0A54_09749

0.673

B0A54_00595

0.664

B0A54_01226

0.664

B0A54_06239

0.655

B0A54_03143

0.655

B0A54_15974

0.640

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_00595	B0A54_17066	A0A4U0VH11	A0A4U0TXP8	Uncharacterized protein.	Uncharacterized protein.	0.664
B0A54_01226	B0A54_17066	A0A4U0VIS5	A0A4U0TXP8	SMN domain-containing protein.	Uncharacterized protein.	0.664
B0A54_03143	B0A54_05127	A0A4U0V8D1	A0A4U0V748	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_03143	B0A54_09749	A0A4U0V8D1	A0A4U0UPQ7	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_03143	B0A54_10136	A0A4U0V8D1	A0A4U0UU80	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_03143	B0A54_15974	A0A4U0V8D1	A0A4U0U227	DNA polymerase.	ERCC4 domain-containing protein; Belongs to the histidine acid phosphatase family.	0.730
B0A54_03143	B0A54_17066	A0A4U0V8D1	A0A4U0TXP8	DNA polymerase.	Uncharacterized protein.	0.655
B0A54_05127	B0A54_03143	A0A4U0V748	A0A4U0V8D1	Uncharacterized protein.	DNA polymerase.	0.998
B0A54_05127	B0A54_06239	A0A4U0V748	A0A4U0UYZ9	Uncharacterized protein.	DNA polymerase.	0.998
B0A54_05127	B0A54_09749	A0A4U0V748	A0A4U0UPQ7	Uncharacterized protein.	Uncharacterized protein.	0.998
B0A54_05127	B0A54_17066	A0A4U0V748	A0A4U0TXP8	Uncharacterized protein.	Uncharacterized protein.	0.684
B0A54_06239	B0A54_05127	A0A4U0UYZ9	A0A4U0V748	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_06239	B0A54_09749	A0A4U0UYZ9	A0A4U0UPQ7	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_06239	B0A54_10136	A0A4U0UYZ9	A0A4U0UU80	DNA polymerase.	Uncharacterized protein.	0.998
B0A54_06239	B0A54_15974	A0A4U0UYZ9	A0A4U0U227	DNA polymerase.	ERCC4 domain-containing protein; Belongs to the histidine acid phosphatase family.	0.730
B0A54_06239	B0A54_17066	A0A4U0UYZ9	A0A4U0TXP8	DNA polymerase.	Uncharacterized protein.	0.655
B0A54_07042	B0A54_17066	A0A4U0V4S4	A0A4U0TXP8	Uncharacterized protein.	Uncharacterized protein.	0.676
B0A54_09749	B0A54_03143	A0A4U0UPQ7	A0A4U0V8D1	Uncharacterized protein.	DNA polymerase.	0.998
B0A54_09749	B0A54_05127	A0A4U0UPQ7	A0A4U0V748	Uncharacterized protein.	Uncharacterized protein.	0.998
B0A54_09749	B0A54_06239	A0A4U0UPQ7	A0A4U0UYZ9	Uncharacterized protein.	DNA polymerase.	0.998

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

48

average node degree:

8.73

avg. local clustering coefficient:

0.882

expected number of edges:

14

PPI enrichment p-value:

2.36e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 105

1.18

1.73

1.89e-10

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 54

1.42

2.55

2.74e-11

GO:0019843

rRNA binding

8 of 40

1.46

2.33

9.08e-09

GO:0003723

RNA binding

9 of 99

1.11

1.4

1.28e-07

GO:0003676

Nucleic acid binding

10 of 282

0.7

0.64

3.33e-05

GO:0000049

tRNA binding

3 of 24

1.25

0.63

0.0375

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 57

1.4

2.52

8.87e-12

GO:0015935

Small ribosomal subunit

3 of 7

1.79

1.59

0.00043

GO:0005622

Intracellular anatomical structure

11 of 739

0.33

0.29

0.0029

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:71

Structural constituent of ribosome

7 of 22

1.66

2.97

2.37e-09

CL:67

Ribosomal protein

10 of 49

1.46

2.82

2.24e-12

CL:69

Structural constituent of ribosome

9 of 41

1.5

2.79

3.45e-11

CL:65

Ribosomal protein

11 of 63

1.4

2.63

3.90e-13

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 57

1.4

2.52

9.87e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 45

1.35

1.75

1.41e-06

GOCC:0022626

Cytosolic ribosome

3 of 17

1.4

0.95

0.0066

GOCC:0043229

Intracellular organelle

9 of 181

0.85

0.83

1.66e-05

GOCC:0044391

Ribosomal subunit

3 of 23

1.27

0.79

0.0128

GOCC:0005622

Intracellular

11 of 670

0.37

0.31

0.0026

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 55

1.41

2.56

1.16e-11

KW-0699

rRNA-binding

8 of 39

1.47

2.44

2.71e-09

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