B0A54_15927 protein (Friedmanniomyces endolithicus)

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Known Interactions

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Predicted Interactions

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gene co-occurrence

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Score

B0A54_15927

Response regulatory domain-containing protein. (637 aa)

Predicted Functional Partners:

B0A54_13515

0.990

B0A54_04933

0.990

B0A54_17206

0.972

B0A54_12456

0.972

B0A54_07412

0.972

B0A54_05348

0.972

B0A54_03293

0.972

B0A54_13377

0.972

B0A54_09367

0.969

B0A54_14873

0.961

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_03293	B0A54_09367	A0A4U0V839	A0A4U0UWC5	Heat shock protein 90.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.647
B0A54_03293	B0A54_14873	A0A4U0V839	A0A4U0UH08	Heat shock protein 90.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.684
B0A54_03293	B0A54_15927	A0A4U0V839	A0A4U0U362	Heat shock protein 90.	Response regulatory domain-containing protein.	0.972
B0A54_04933	B0A54_14873	A0A4U0V886	A0A4U0UH08	HPt domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.727
B0A54_04933	B0A54_15927	A0A4U0V886	A0A4U0U362	HPt domain-containing protein.	Response regulatory domain-containing protein.	0.990
B0A54_05348	B0A54_09367	A0A4U0V6R3	A0A4U0UWC5	Flavin_Reduct domain-containing protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.647
B0A54_05348	B0A54_14873	A0A4U0V6R3	A0A4U0UH08	Flavin_Reduct domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.684
B0A54_05348	B0A54_15927	A0A4U0V6R3	A0A4U0U362	Flavin_Reduct domain-containing protein.	Response regulatory domain-containing protein.	0.972
B0A54_07412	B0A54_09367	A0A4U0V1T4	A0A4U0UWC5	Flavin_Reduct domain-containing protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.647
B0A54_07412	B0A54_14873	A0A4U0V1T4	A0A4U0UH08	Flavin_Reduct domain-containing protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.684
B0A54_07412	B0A54_15927	A0A4U0V1T4	A0A4U0U362	Flavin_Reduct domain-containing protein.	Response regulatory domain-containing protein.	0.972
B0A54_09367	B0A54_03293	A0A4U0UWC5	A0A4U0V839	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock protein 90.	0.647
B0A54_09367	B0A54_05348	A0A4U0UWC5	A0A4U0V6R3	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Flavin_Reduct domain-containing protein.	0.647
B0A54_09367	B0A54_07412	A0A4U0UWC5	A0A4U0V1T4	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Flavin_Reduct domain-containing protein.	0.647
B0A54_09367	B0A54_12456	A0A4U0UWC5	A0A4U0UMI6	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Heat shock protein 90.	0.647
B0A54_09367	B0A54_13377	A0A4U0UWC5	A0A4V5N6C1	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Uncharacterized protein.	0.647
B0A54_09367	B0A54_15927	A0A4U0UWC5	A0A4U0U362	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Response regulatory domain-containing protein.	0.969
B0A54_09367	B0A54_17206	A0A4U0UWC5	A0A4U0TSV9	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	Uncharacterized protein.	0.647
B0A54_12456	B0A54_09367	A0A4U0UMI6	A0A4U0UWC5	Heat shock protein 90.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.647
B0A54_12456	B0A54_14873	A0A4U0UMI6	A0A4U0UH08	Heat shock protein 90.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.684

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

30

PPI enrichment p-value:

1.11e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 112

1.47

2.94

1.52e-13

GO:0006418

tRNA aminoacylation for protein translation

4 of 24

1.7

1.79

8.29e-05

GO:0006432

phenylalanyl-tRNA aminoacylation

2 of 3

2.3

1.27

0.0044

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

5 of 43

1.54

1.71

5.00e-05

GO:0003723

RNA binding

8 of 123

1.29

1.7

4.96e-07

GO:0004812

aminoacyl-tRNA ligase activity

4 of 27

1.64

1.58

0.00026

GO:0003735

Structural constituent of ribosome

5 of 56

1.42

1.47

0.00013

GO:0004826

phenylalanine-tRNA ligase activity

2 of 3

2.3

1.22

0.0054

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

5 of 61

1.39

1.4

0.00016

GO:0005622

Intracellular anatomical structure

11 of 1143

0.46

0.38

0.00066

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:106

Translation, and Protein export

11 of 157

1.32

2.29

3.30e-12

CL:374

Aminoacyl-tRNA synthetase

4 of 16

1.87

2.2

1.67e-05

CL:125

Structural constituent of ribosome

5 of 33

1.65

2.13

5.22e-06

CL:123

Structural constituent of ribosome

6 of 66

1.43

1.82

4.07e-06

CL:110

Ribosome, and Translation regulator activity

7 of 97

1.33

1.73

1.41e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

drm03010

Ribosome

5 of 57

1.42

1.5

8.59e-05

drm00970

Aminoacyl-tRNA biosynthesis

3 of 28

1.5

1.01

0.0060

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

4 of 46

1.41

1.12

0.0021

GOCC:0005737

Cytoplasm

9 of 735

0.56

0.42

0.0048

GOCC:0005622

Intracellular

11 of 1119

0.47

0.37

0.0021

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0694

RNA-binding

8 of 79

1.48

2.43

5.37e-09

KW-0648

Protein biosynthesis

6 of 49

1.56

2.21

7.17e-07

KW-0699

rRNA-binding

5 of 41

1.56

1.9

1.24e-05

KW-0030

Aminoacyl-tRNA synthetase

4 of 24

1.7

1.83

6.33e-05

KW-0820

tRNA-binding

3 of 13

1.84

1.62

0.00043

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF01588

Putative tRNA binding domain

2 of 2

2.47

0.81

0.0333

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