node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0A54_03062 | B0A54_06706 | A0A4U0VDT6 | A0A4U0V2Y9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-1 domain-containing protein. | 0.745 |
B0A54_03062 | B0A54_09127 | A0A4U0VDT6 | A0A4U0UQS3 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.928 |
B0A54_03062 | B0A54_11390 | A0A4U0VDT6 | A0A4U0UPQ9 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-1 domain-containing protein. | 0.745 |
B0A54_03062 | B0A54_12422 | A0A4U0VDT6 | A0A4U0UKZ3 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Bifunctional purine biosynthesis protein ADE17. | 0.974 |
B0A54_03062 | B0A54_12964 | A0A4U0VDT6 | A0A4U0UM04 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Uncharacterized protein. | 0.775 |
B0A54_03062 | B0A54_15488 | A0A4U0VDT6 | A0A4U0UBR5 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP synthase [glutamine-hydrolyzing]. | 0.698 |
B0A54_03062 | B0A54_15582 | A0A4U0VDT6 | A0A4U0UB07 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | GMP synthase [glutamine-hydrolyzing]. | 0.698 |
B0A54_03062 | B0A54_16668 | A0A4U0VDT6 | A0A4U0TWG0 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.987 |
B0A54_03062 | B0A54_17071 | A0A4U0VDT6 | A0A4U0TUK0 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.987 |
B0A54_06706 | B0A54_03062 | A0A4U0V2Y9 | A0A4U0VDT6 | Glutamine amidotransferase type-1 domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.745 |
B0A54_06706 | B0A54_09127 | A0A4U0V2Y9 | A0A4U0UQS3 | Glutamine amidotransferase type-1 domain-containing protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.846 |
B0A54_06706 | B0A54_09146 | A0A4U0V2Y9 | A0A4U0USZ5 | Glutamine amidotransferase type-1 domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.745 |
B0A54_06706 | B0A54_12422 | A0A4U0V2Y9 | A0A4U0UKZ3 | Glutamine amidotransferase type-1 domain-containing protein. | Bifunctional purine biosynthesis protein ADE17. | 0.606 |
B0A54_06706 | B0A54_12964 | A0A4U0V2Y9 | A0A4U0UM04 | Glutamine amidotransferase type-1 domain-containing protein. | Uncharacterized protein. | 0.833 |
B0A54_06706 | B0A54_15488 | A0A4U0V2Y9 | A0A4U0UBR5 | Glutamine amidotransferase type-1 domain-containing protein. | GMP synthase [glutamine-hydrolyzing]. | 0.802 |
B0A54_06706 | B0A54_15582 | A0A4U0V2Y9 | A0A4U0UB07 | Glutamine amidotransferase type-1 domain-containing protein. | GMP synthase [glutamine-hydrolyzing]. | 0.802 |
B0A54_06706 | B0A54_16668 | A0A4U0V2Y9 | A0A4U0TWG0 | Glutamine amidotransferase type-1 domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.980 |
B0A54_06706 | B0A54_17071 | A0A4U0V2Y9 | A0A4U0TUK0 | Glutamine amidotransferase type-1 domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.980 |
B0A54_09127 | B0A54_03062 | A0A4U0UQS3 | A0A4U0VDT6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP. | 0.928 |
B0A54_09127 | B0A54_06706 | A0A4U0UQS3 | A0A4U0V2Y9 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamine amidotransferase type-1 domain-containing protein. | 0.846 |