STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NBP35Cytosolic Fe-S cluster assembly factor NBP35; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. (343 aa)    
Predicted Functional Partners:
B0A54_02071
Histidine biosynthesis trifunctional protein.
    
 0.816
B0A54_06406
Histidine biosynthesis trifunctional protein.
    
 0.816
B0A54_10452
Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.
   
 0.773
B0A54_05267
Fe_hyd_lg_C domain-containing protein; Belongs to the NARF family.
   
 0.773
B0A54_12654
Iron-sulfur clusters transporter atm1, mitochondrial.
    
 0.761
B0A54_03284
Iron-sulfur clusters transporter atm1, mitochondrial.
    
 0.761
B0A54_11549
DRE2_N domain-containing protein.
   
 0.740
DRE2
Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...]
   
 0.740
B0A54_04077
NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial.
  
 
 0.721
B0A54_02537
NADH-ubiquinone oxidoreductase 23 kDa subunit, mitochondrial.
  
 
 0.721
Your Current Organism:
Friedmanniomyces endolithicus
NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.