B0A54_11043 protein (Friedmanniomyces endolithicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A54_11043

Uncharacterized protein. (850 aa)

Predicted Functional Partners:

B0A54_01999

0.879

B0A54_08411

0.878

B0A54_04840

0.871

B0A54_01907

0.871

B0A54_03623

0.865

B0A54_02152

0.865

B0A54_07606

0.832

B0A54_02348

0.832

B0A54_10525

0.826

B0A54_10524

0.826

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_01907	B0A54_01999	A0A4U0VH30	A0A4U0VH97	Peroxisomal hydratase-dehydrogenase-epimerase.	AMP-binding domain-containing protein.	0.699
B0A54_01907	B0A54_08411	A0A4U0VH30	A0A4U0UUQ7	Peroxisomal hydratase-dehydrogenase-epimerase.	AMP-binding domain-containing protein.	0.699
B0A54_01907	B0A54_11043	A0A4U0VH30	A0A4U0UNM7	Peroxisomal hydratase-dehydrogenase-epimerase.	Uncharacterized protein.	0.871
B0A54_01999	B0A54_01907	A0A4U0VH97	A0A4U0VH30	AMP-binding domain-containing protein.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.699
B0A54_01999	B0A54_02152	A0A4U0VH97	A0A4U0VFH4	AMP-binding domain-containing protein.	Uncharacterized protein.	0.853
B0A54_01999	B0A54_02348	A0A4U0VH97	A0A4U0VEC8	AMP-binding domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.626
B0A54_01999	B0A54_03623	A0A4U0VH97	A0A4U0VAI1	AMP-binding domain-containing protein.	Uncharacterized protein.	0.853
B0A54_01999	B0A54_04840	A0A4U0VH97	A0A4U0V5U4	AMP-binding domain-containing protein.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.699
B0A54_01999	B0A54_07606	A0A4U0VH97	A0A4U0V0I4	AMP-binding domain-containing protein.	Uncharacterized protein; Belongs to the peptidase C19 family.	0.626
B0A54_01999	B0A54_10524	A0A4U0VH97	A0A4U0URB1	AMP-binding domain-containing protein.	PKS_AT domain-containing protein; Belongs to the fungal fatty acid synthetase subunit beta family.	0.827
B0A54_01999	B0A54_10525	A0A4U0VH97	A0A4U0UQF8	AMP-binding domain-containing protein.	Fatty acid synthase subunit alpha; Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.	0.827
B0A54_01999	B0A54_11043	A0A4U0VH97	A0A4U0UNM7	AMP-binding domain-containing protein.	Uncharacterized protein.	0.879
B0A54_02152	B0A54_01999	A0A4U0VFH4	A0A4U0VH97	Uncharacterized protein.	AMP-binding domain-containing protein.	0.853
B0A54_02152	B0A54_08411	A0A4U0VFH4	A0A4U0UUQ7	Uncharacterized protein.	AMP-binding domain-containing protein.	0.853
B0A54_02152	B0A54_11043	A0A4U0VFH4	A0A4U0UNM7	Uncharacterized protein.	Uncharacterized protein.	0.865
B0A54_02348	B0A54_01999	A0A4U0VEC8	A0A4U0VH97	Uncharacterized protein; Belongs to the peptidase C19 family.	AMP-binding domain-containing protein.	0.626
B0A54_02348	B0A54_08411	A0A4U0VEC8	A0A4U0UUQ7	Uncharacterized protein; Belongs to the peptidase C19 family.	AMP-binding domain-containing protein.	0.626
B0A54_02348	B0A54_11043	A0A4U0VEC8	A0A4U0UNM7	Uncharacterized protein; Belongs to the peptidase C19 family.	Uncharacterized protein.	0.832
B0A54_03623	B0A54_01999	A0A4U0VAI1	A0A4U0VH97	Uncharacterized protein.	AMP-binding domain-containing protein.	0.853
B0A54_03623	B0A54_08411	A0A4U0VAI1	A0A4U0UUQ7	Uncharacterized protein.	AMP-binding domain-containing protein.	0.853

page 1 of 3

Network Stats

number of nodes:

2

number of edges:

1

average node degree:

1

avg. local clustering coefficient:

1

expected number of edges:

1

PPI enrichment p-value:

0.5

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000105

Histidine biosynthetic process

5 of 13

2.3

3.87

1.46e-08

GO:0009073

Aromatic amino acid family biosynthetic process

4 of 17

2.08

2.57

5.44e-06

GO:0008652

Cellular amino acid biosynthetic process

9 of 183

1.4

2.25

3.71e-09

GO:0006520

Cellular amino acid metabolic process

10 of 311

1.22

1.76

3.71e-09

GO:0009095

Aromatic amino acid family biosynthetic process, prephenate pathway

2 of 2

2.71

1.56

0.0014

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016836

Hydro-lyase activity

3 of 38

1.61

0.67

0.0478

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1823

0.45

0.33

0.0134

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1575

Aromatic amino acid family biosynthetic process, and Histidine biosynthesis

8 of 28

2.17

5.69

6.02e-14

CL:1515

Amino-acid biosynthesis, and Aminotransferase class IV

10 of 58

1.95

5.46

4.37e-16

CL:1608

Histidine biosynthesis

5 of 10

2.41

4.15

6.00e-09

CL:1611

Histidine biosynthesis

3 of 5

2.49

2.28

5.48e-05

CL:1576

Aromatic amino acid family biosynthetic process

3 of 16

1.98

1.56

0.00082

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00400

Phenylalanine, tyrosine and tryptophan biosynthesis

5 of 25

2.01

3.21

8.92e-08

map00340

Histidine metabolism

5 of 29

1.95

3.08

1.16e-07

map01230

Biosynthesis of amino acids

9 of 231

1.3

1.99

2.63e-09

map00401

Novobiocin biosynthesis

2 of 3

2.53

1.69

0.00076

map00360

Phenylalanine metabolism

3 of 36

1.63

1.37

0.00092

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005737

Cytoplasm

11 of 1419

0.6

0.52

8.49e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0368

Histidine biosynthesis

5 of 12

2.33

4.05

6.80e-09

KW-0028

Amino-acid biosynthesis

8 of 88

1.67

3.22

1.88e-10

KW-0057

Aromatic amino acid biosynthesis

3 of 14

2.04

1.79

0.00028

KW-0822

Tryptophan biosynthesis

2 of 6

2.23

1.26

0.0044

KW-0456

Lyase

4 of 110

1.27

0.99

0.0027

(more ...)

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (30%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About