B0A54_11111 protein (Friedmanniomyces endolithicus)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

B0A54_11111

EHN domain-containing protein. (403 aa)

Predicted Functional Partners:

B0A54_13546

0.781

B0A54_04962

0.781

B0A54_11115

0.703

B0A54_15705

0.700

B0A54_13307

0.700

B0A54_12575

0.700

B0A54_13026

0.700

B0A54_02912

0.700

B0A54_04083

0.653

B0A54_02543

0.653

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_02543	B0A54_02912	A0A4U0VFW2	A0A4U0VDE8	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.578
B0A54_02543	B0A54_11111	A0A4U0VFW2	A0A4U0UQJ6	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	EHN domain-containing protein.	0.653
B0A54_02543	B0A54_12575	A0A4U0VFW2	A0A4U0UJF5	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578
B0A54_02543	B0A54_13026	A0A4U0VFW2	A0A4U0UKL3	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578
B0A54_02543	B0A54_13307	A0A4U0VFW2	A0A4U0UH51	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578
B0A54_02543	B0A54_15705	A0A4U0VFW2	A0A4U0UA65	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.578
B0A54_02912	B0A54_02543	A0A4U0VDE8	A0A4U0VFW2	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.578
B0A54_02912	B0A54_04083	A0A4U0VDE8	A0A4U0V9N0	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.578
B0A54_02912	B0A54_04962	A0A4U0VDE8	A0A4U0V8I8	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Tryptophan synthase.	0.860
B0A54_02912	B0A54_11111	A0A4U0VDE8	A0A4U0UQJ6	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	EHN domain-containing protein.	0.700
B0A54_02912	B0A54_12575	A0A4U0VDE8	A0A4U0UJF5	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_13026	A0A4U0VDE8	A0A4U0UKL3	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_13307	A0A4U0VDE8	A0A4U0UH51	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_13546	A0A4U0VDE8	A0A4U0ULH7	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Tryptophan synthase.	0.860
B0A54_02912	B0A54_15705	A0A4U0VDE8	A0A4U0UA65	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.868
B0A54_04083	B0A54_02912	A0A4U0V9N0	A0A4U0VDE8	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.578
B0A54_04083	B0A54_11111	A0A4U0V9N0	A0A4U0UQJ6	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	EHN domain-containing protein.	0.653
B0A54_04083	B0A54_12575	A0A4U0V9N0	A0A4U0UJF5	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578
B0A54_04083	B0A54_13026	A0A4U0V9N0	A0A4U0UKL3	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578
B0A54_04083	B0A54_13307	A0A4U0V9N0	A0A4U0UH51	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Uncharacterized protein.	0.578

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

24

average node degree:

4.36

avg. local clustering coefficient:

0.901

expected number of edges:

11

PPI enrichment p-value:

0.000451

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006289

Nucleotide-excision repair

3 of 5

2.28

1.79

0.00041

GO:0033554

Cellular response to stress

6 of 78

1.39

1.47

8.68e-05

GO:0006281

DNA repair

5 of 54

1.47

1.43

0.00026

GO:0009432

SOS response

3 of 15

1.8

1.22

0.0034

GO:0006308

DNA catabolic process

2 of 5

2.1

1.01

0.0128

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004536

Deoxyribonuclease activity

4 of 23

1.74

1.5

0.00063

GO:0008855

Exodeoxyribonuclease VII activity

2 of 2

2.5

1.16

0.0076

GO:0009381

Excinuclease ABC activity

2 of 3

2.33

1.11

0.0090

GO:0140097

Catalytic activity, acting on DNA

5 of 105

1.18

0.88

0.0039

GO:0140640

Catalytic activity, acting on a nucleic acid

6 of 242

0.9

0.63

0.0071

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009318

Exodeoxyribonuclease VII complex

2 of 2

2.5

1.32

0.0037

GO:0009380

Excinuclease repair complex

2 of 3

2.33

1.28

0.0041

GO:1902494

Catalytic complex

5 of 80

1.3

1.21

0.00043

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:617

DNA damage, and UvrD/REP helicase N-terminal domain

3 of 21

1.66

0.72

0.0372

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

tor03420

Nucleotide excision repair

3 of 9

2.03

1.66

0.00053

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990391

DNA repair complex

3 of 6

2.2

1.69

0.00058

GOCC:0009318

Exodeoxyribonuclease VII complex

2 of 2

2.5

1.14

0.0081

GOCC:0009380

Excinuclease repair complex

2 of 3

2.33

1.11

0.0090

GOCC:1902494

Catalytic complex

5 of 192

0.92

0.6

0.0141

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0234

DNA repair

5 of 29

1.74

2.22

6.15e-06

KW-0742

SOS response

3 of 10

1.98

1.67

0.00047

KW-0267

Excision nuclease

2 of 3

2.33

1.24

0.0049

KW-0228

DNA excision

2 of 3

2.33

1.24

0.0049

KW-0269

Exonuclease

2 of 15

1.63

0.74

0.0341

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02151

UvrB/uvrC motif

2 of 2

2.5

0.84

0.0295

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00278

Helix-hairpin-helix DNA-binding motif class 1

2 of 8

1.9

0.7

0.0465

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