STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (449 aa)    
Predicted Functional Partners:
B0A54_13458
Dynein heavy chain, cytoplasmic.
    
 0.995
B0A54_06620
Dynein heavy chain, cytoplasmic.
    
 0.995
B0A54_08270
NUDE_C domain-containing protein.
    
 
 0.950
B0A54_02804
NUDE_C domain-containing protein.
    
 
 0.950
B0A54_08240
Uncharacterized protein.
   
 0.948
B0A54_10996
WD_REPEATS_REGION domain-containing protein.
   
 0.916
B0A54_04621
WD_REPEATS_REGION domain-containing protein.
   
 0.916
B0A54_12442
Nuclear movement protein nudC.
    
 0.915
B0A54_12203
Nuclear movement protein nudC.
    
 0.915
B0A54_09435
Uncharacterized protein.
    
 0.897
Your Current Organism:
Friedmanniomyces endolithicus
NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus
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