B0A54_04323 protein (Friedmanniomyces endolithicus)

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Known Interactions

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Predicted Interactions

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Score

B0A54_04323

Uncharacterized protein; Belongs to the CDC50/LEM3 family. (423 aa)

Predicted Functional Partners:

B0A54_17347

0.952

B0A54_10795

0.952

B0A54_03941

0.927

B0A54_03905

0.927

B0A54_05806

0.837

B0A54_05202

0.837

B0A54_16512

0.768

B0A54_13724

0.768

B0A54_12750

0.768

B0A54_11104

0.768

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_03905	B0A54_04323	A0A4V5N9J7	A0A4U0V8U8	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	0.927
B0A54_03905	B0A54_10795	A0A4V5N9J7	A0A4V5N7M5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.579
B0A54_03905	B0A54_11104	A0A4V5N9J7	A0A4U0UQF4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03905	B0A54_12750	A0A4V5N9J7	A0A4U0UM64	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03905	B0A54_13724	A0A4V5N9J7	A0A4U0UHC5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03905	B0A54_16512	A0A4V5N9J7	A0A4U0U2A8	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03905	B0A54_17347	A0A4V5N9J7	A0A4U0TUW9	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	P-type phospholipid transporter.	0.579
B0A54_03941	B0A54_04323	A0A4U0VFP1	A0A4U0V8U8	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	0.927
B0A54_03941	B0A54_10795	A0A4U0VFP1	A0A4V5N7M5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.579
B0A54_03941	B0A54_11104	A0A4U0VFP1	A0A4U0UQF4	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03941	B0A54_12750	A0A4U0VFP1	A0A4U0UM64	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03941	B0A54_13724	A0A4U0VFP1	A0A4U0UHC5	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03941	B0A54_16512	A0A4U0VFP1	A0A4U0U2A8	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.406
B0A54_03941	B0A54_17347	A0A4U0VFP1	A0A4U0TUW9	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	P-type phospholipid transporter.	0.579
B0A54_04323	B0A54_03905	A0A4U0V8U8	A0A4V5N9J7	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.927
B0A54_04323	B0A54_03941	A0A4U0V8U8	A0A4U0VFP1	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.927
B0A54_04323	B0A54_05202	A0A4U0V8U8	A0A4U0V6P3	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Uncharacterized protein.	0.837
B0A54_04323	B0A54_05806	A0A4U0V8U8	A0A4U0V6A2	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Uncharacterized protein.	0.837
B0A54_04323	B0A54_10795	A0A4U0V8U8	A0A4V5N7M5	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.952
B0A54_04323	B0A54_11104	A0A4U0V8U8	A0A4U0UQF4	Uncharacterized protein; Belongs to the CDC50/LEM3 family.	Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.	0.768

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Network Stats

number of nodes:

5

number of edges:

8

average node degree:

3.2

avg. local clustering coefficient:

0.867

expected number of edges:

4

PPI enrichment p-value:

0.0581

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

4 of 12

1.84

1.58

0.00052

GO:0034654

Nucleobase-containing compound biosynthetic process

5 of 121

0.93

0.5

0.0423

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003899

DNA-directed 5-3 RNA polymerase activity

4 of 6

2.14

2.25

3.45e-05

GO:0016779

Nucleotidyltransferase activity

5 of 69

1.17

0.99

0.0012

GO:0003677

DNA binding

7 of 182

0.9

0.75

0.00086

GO:0140640

Catalytic activity, acting on a nucleic acid

7 of 196

0.87

0.71

0.0011

GO:1901363

Heterocyclic compound binding

9 of 653

0.45

0.31

0.0306

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000428

DNA-directed RNA polymerase complex

4 of 7

2.07

2.42

1.14e-05

GO:0032991

Protein-containing complex

5 of 191

0.73

0.46

0.0229

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:289

RNA polymerase, and Nucleotide excision repair

6 of 7

2.25

4.17

2.06e-09

CL:97

Ribosome, and Protein export

8 of 105

1.2

1.48

1.07e-06

CL:618

Mixed, incl. WD40-repeat-containing domain superfamily, and ANK repeat

3 of 16

1.59

1.1

0.0044

CL:620

Mixed, incl. WD40-repeat-containing domain superfamily, and ANK repeat

2 of 7

1.77

0.77

0.0315

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03020

RNA polymerase

4 of 4

2.31

2.9

2.18e-06

map03420

Nucleotide excision repair

3 of 13

1.68

1.24

0.0024

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9635486

Infection with Mycobacterium tuberculosis

4 of 44

1.27

1.06

0.0014

MAP-5663205

Infectious disease

4 of 47

1.24

1.04

0.0014

MAP-1643685

Disease

4 of 52

1.2

1.0

0.0014

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0031931

TORC1 complex

3 of 5

2.09

1.55

0.0010

GOCC:0000428

DNA-directed RNA polymerase complex

4 of 28

1.47

1.25

0.0010

GOCC:0032991

Protein-containing complex

8 of 367

0.65

0.51

0.0019

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0240

DNA-directed RNA polymerase

4 of 7

2.07

2.32

1.96e-05

KW-0548

Nucleotidyltransferase

5 of 36

1.46

1.58

6.43e-05

KW-0853

WD repeat

2 of 2

2.31

1.18

0.0064

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036322

WD40-repeat-containing domain superfamily

3 of 4

2.19

1.35

0.0028

IPR015943

WD40/YVTN repeat-like-containing domain superfamily

3 of 4

2.19

1.35

0.0028

IPR001680

WD40 repeat

2 of 2

2.31

0.76

0.0412

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00320

WD40 repeats

2 of 2

2.31

1.08

0.0102

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