B0A54_04466 protein (Friedmanniomyces endolithicus)

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Known Interactions

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Predicted Interactions

gene neighborhood

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Score

B0A54_04466

ThiF domain-containing protein. (511 aa)

Predicted Functional Partners:

B0A54_12100

0.779

B0A54_03493

0.779

B0A54_15297

0.773

B0A54_14877

0.773

B0A54_13063

0.773

B0A54_03420

0.773

hxB

0.721

hxB-2

0.721

B0A54_10453

0.721

B0A54_10248

0.721

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_03420	B0A54_03493	A0A4U0VCG4	A0A4U0VA63	Aminotran_5 domain-containing protein.	Rhodanese domain-containing protein.	0.867
B0A54_03420	B0A54_04466	A0A4U0VCG4	A0A4U0V920	Aminotran_5 domain-containing protein.	ThiF domain-containing protein.	0.773
B0A54_03420	B0A54_10248	A0A4U0VCG4	A0A4U0UV33	Aminotran_5 domain-containing protein.	Aminotran_5 domain-containing protein.	0.697
B0A54_03420	B0A54_10453	A0A4U0VCG4	A0A4U0UTW0	Aminotran_5 domain-containing protein.	Uncharacterized protein.	0.697
B0A54_03420	B0A54_12100	A0A4U0VCG4	A0A4U0UIG5	Aminotran_5 domain-containing protein.	Rhodanese domain-containing protein.	0.867
B0A54_03420	B0A54_13063	A0A4U0VCG4	A0A4U0UKF7	Aminotran_5 domain-containing protein.	Cysteine desulfurase, mitochondrial.	0.436
B0A54_03420	B0A54_15297	A0A4U0VCG4	A0A4U0U991	Aminotran_5 domain-containing protein.	Cysteine desulfurase, mitochondrial.	0.436
B0A54_03420	hxB	A0A4U0VCG4	A0A4U0TYX0	Aminotran_5 domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.697
B0A54_03420	hxB-2	A0A4U0VCG4	A0A4U0UI81	Aminotran_5 domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.697
B0A54_03493	B0A54_03420	A0A4U0VA63	A0A4U0VCG4	Rhodanese domain-containing protein.	Aminotran_5 domain-containing protein.	0.867
B0A54_03493	B0A54_04466	A0A4U0VA63	A0A4U0V920	Rhodanese domain-containing protein.	ThiF domain-containing protein.	0.779
B0A54_03493	B0A54_10248	A0A4U0VA63	A0A4U0UV33	Rhodanese domain-containing protein.	Aminotran_5 domain-containing protein.	0.676
B0A54_03493	B0A54_10453	A0A4U0VA63	A0A4U0UTW0	Rhodanese domain-containing protein.	Uncharacterized protein.	0.676
B0A54_03493	B0A54_13063	A0A4U0VA63	A0A4U0UKF7	Rhodanese domain-containing protein.	Cysteine desulfurase, mitochondrial.	0.867
B0A54_03493	B0A54_14877	A0A4U0VA63	A0A4U0UEN9	Rhodanese domain-containing protein.	Aminotran_5 domain-containing protein.	0.867
B0A54_03493	B0A54_15297	A0A4U0VA63	A0A4U0U991	Rhodanese domain-containing protein.	Cysteine desulfurase, mitochondrial.	0.867
B0A54_03493	hxB	A0A4U0VA63	A0A4U0TYX0	Rhodanese domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.676
B0A54_03493	hxB-2	A0A4U0VA63	A0A4U0UI81	Rhodanese domain-containing protein.	Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.	0.676
B0A54_04466	B0A54_03420	A0A4U0V920	A0A4U0VCG4	ThiF domain-containing protein.	Aminotran_5 domain-containing protein.	0.773
B0A54_04466	B0A54_03493	A0A4U0V920	A0A4U0VA63	ThiF domain-containing protein.	Rhodanese domain-containing protein.	0.779

page 1 of 5

Network Stats

number of nodes:

10

number of edges:

29

average node degree:

5.8

avg. local clustering coefficient:

0.756

expected number of edges:

9

PPI enrichment p-value:

1.72e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0002181

Cytoplasmic translation

4 of 76

2.16

2.59

6.63e-06

GO:0006412

Translation

8 of 604

1.56

2.53

1.93e-08

GO:0044271

Cellular nitrogen compound biosynthetic process

9 of 1524

1.21

1.62

8.34e-08

GO:0009059

Macromolecule biosynthetic process

9 of 1591

1.19

1.58

9.16e-08

GO:0042273

Ribosomal large subunit biogenesis

3 of 86

1.98

1.52

0.0010

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 283

1.94

4.89

8.04e-14

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044391

Ribosomal subunit

9 of 216

2.06

5.81

1.40e-15

GO:0022626

Cytosolic ribosome

8 of 167

2.12

5.57

5.01e-14

GO:0005840

Ribosome

10 of 335

1.91

5.33

3.12e-16

GO:0022625

Cytosolic large ribosomal subunit

5 of 103

2.12

3.55

2.91e-08

GO:0015935

Small ribosomal subunit

4 of 90

2.08

2.7

2.66e-06

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:13943

Cytosolic large ribosomal subunit

7 of 16

3.08

8.55

1.00e-16

CL:13922

Cytosolic ribosome

8 of 55

2.6

7.89

1.00e-16

CL:13917

Cytosolic ribosome

9 of 120

2.31

7.11

1.00e-16

CL:13946

Cytoplasmic translation, and Ribosomal protein L27e

5 of 11

3.09

6.23

3.16e-12

CL:13949

Mixed, incl. Ribosomal protein L36e, and Ribosomal protein L27e

2 of 5

3.04

1.72

0.00077

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 457

1.78

4.58

1.26e-15

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72706

GTP hydrolysis and joining of the 60S ribosomal subunit

9 of 237

2.02

5.47

6.41e-15

MAP-975956

Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)

9 of 240

2.01

5.45

6.41e-15

MAP-72689

Formation of a pool of free 40S subunits

9 of 255

1.98

5.34

6.41e-15

MAP-1799339

SRP-dependent cotranslational protein targeting to membrane

9 of 260

1.98

5.31

6.41e-15

MAP-975957

Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)

9 of 263

1.97

5.29

6.41e-15

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 189

2.06

5.06

6.36e-13

GOCC:0044391

Ribosomal subunit

7 of 149

2.11

4.7

1.91e-11

GOCC:0022626

Cytosolic ribosome

6 of 130

2.1

4.0

1.54e-09

GOCC:0015935

Small ribosomal subunit

4 of 61

2.25

2.91

1.73e-06

GOCC:0022627

Cytosolic small ribosomal subunit

3 of 44

2.27

2.09

9.74e-05

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

3 of 99

1.92

1.39

0.0017

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