B0A54_02031 protein (Friedmanniomyces endolithicus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

B0A54_02031

Uncharacterized protein. (93 aa)

Predicted Functional Partners:

B0A54_15984

0.937

B0A54_15368

0.937

B0A54_11512

0.883

B0A54_10890

0.883

B0A54_07298

0.883

B0A54_04133

0.883

B0A54_00524

0.883

B0A54_02597

0.883

B0A54_07686

0.808

B0A54_04049

0.808

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_00524	B0A54_02031	A0A4V5N9P2	A0A4U0VEV8	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_00524	B0A54_04049	A0A4V5N9P2	A0A4U0V9E9	Uncharacterized protein.	Uncharacterized protein.	0.608
B0A54_00524	B0A54_07686	A0A4V5N9P2	A0A4U0UYE0	Uncharacterized protein.	PH domain-containing protein.	0.670
B0A54_00524	B0A54_15368	A0A4V5N9P2	A0A4U0U574	Uncharacterized protein.	Uncharacterized protein.	0.605
B0A54_00524	B0A54_15984	A0A4V5N9P2	A0A4U0U232	Uncharacterized protein.	Uncharacterized protein.	0.605
B0A54_02031	B0A54_00524	A0A4U0VEV8	A0A4V5N9P2	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_02597	A0A4U0VEV8	A0A4V5NAB6	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_04049	A0A4U0VEV8	A0A4U0V9E9	Uncharacterized protein.	Uncharacterized protein.	0.808
B0A54_02031	B0A54_04133	A0A4U0VEV8	A0A4U0V9S3	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_07298	A0A4U0VEV8	A0A4U0V0V4	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_07686	A0A4U0VEV8	A0A4U0UYE0	Uncharacterized protein.	PH domain-containing protein.	0.808
B0A54_02031	B0A54_10890	A0A4U0VEV8	A0A4U0UW25	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_11512	A0A4U0VEV8	A0A4U0UP38	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02031	B0A54_15368	A0A4U0VEV8	A0A4U0U574	Uncharacterized protein.	Uncharacterized protein.	0.937
B0A54_02031	B0A54_15984	A0A4U0VEV8	A0A4U0U232	Uncharacterized protein.	Uncharacterized protein.	0.937
B0A54_02597	B0A54_02031	A0A4V5NAB6	A0A4U0VEV8	Uncharacterized protein.	Uncharacterized protein.	0.883
B0A54_02597	B0A54_04049	A0A4V5NAB6	A0A4U0V9E9	Uncharacterized protein.	Uncharacterized protein.	0.608
B0A54_02597	B0A54_07686	A0A4V5NAB6	A0A4U0UYE0	Uncharacterized protein.	PH domain-containing protein.	0.608
B0A54_02597	B0A54_15368	A0A4V5NAB6	A0A4U0U574	Uncharacterized protein.	Uncharacterized protein.	0.514
B0A54_02597	B0A54_15984	A0A4V5NAB6	A0A4U0U232	Uncharacterized protein.	Uncharacterized protein.	0.514

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.847

expected number of edges:

24

PPI enrichment p-value:

0.404

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043161

Proteasome-mediated ubiquitin-dependent protein catabolic process

5 of 240

1.44

1.13

0.0022

GO:0006511

Ubiquitin-dependent protein catabolic process

6 of 410

1.29

1.02

0.0022

GO:0019538

Protein metabolic process

9 of 2939

0.61

0.4

0.0189

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0034657

GID complex

2 of 4

2.82

1.08

0.0112

GO:0000151

Ubiquitin ligase complex

4 of 236

1.35

0.8

0.0155

GO:0140535

Intracellular protein-containing complex

5 of 577

1.06

0.65

0.0180

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:23827

Mixed, incl. CRA domain, and GID complex

7 of 16

2.76

7.26

9.01e-15

CL:23822

Mostly uncharacterized, incl. CRA domain, and Yip1 domain

8 of 55

2.29

6.21

1.94e-14

CL:23831

GID complex, and CRA domain

5 of 10

2.82

5.26

1.31e-10

CL:23834

CRA domain, and GID complex

4 of 5

3.03

4.36

9.84e-09

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034657

GID complex

3 of 4

3.0

2.61

1.80e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR016244

Tyrosine-protein kinase, HGF/MSP receptor

2 of 2

3.12

1.03

0.0142

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00429

Ig-like, plexins, transcription factors

2 of 13

2.31

0.79

0.0352

SM00630

Semaphorin domain

2 of 21

2.1

0.74

0.0423

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (26%) [HD]

Permalink

Credits

Access

Info

About

STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About