B0A54_01190 protein (Friedmanniomyces endolithicus)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

B0A54_01190

Uncharacterized protein. (388 aa)

Predicted Functional Partners:

B0A54_14853

0.744

B0A54_15705

0.671

B0A54_13307

0.671

B0A54_12575

0.671

B0A54_13026

0.671

B0A54_02912

0.671

B0A54_12066

0.637

B0A54_03529

0.637

B0A54_08486

0.627

B0A54_02313

0.623

Your Current Organism:

Friedmanniomyces endolithicus

NCBI taxonomy Id: 329885
Other names: CCFEE 5208, F. endolithicus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A54_01190	B0A54_02313	A0A4U0VIW1	A0A4U0VBZ9	Uncharacterized protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.623
B0A54_01190	B0A54_02912	A0A4U0VIW1	A0A4U0VDE8	Uncharacterized protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.671
B0A54_01190	B0A54_03529	A0A4U0VIW1	A0A4U0VAE2	Uncharacterized protein.	Uncharacterized protein.	0.637
B0A54_01190	B0A54_08486	A0A4U0VIW1	A0A4U0UT89	Uncharacterized protein.	Uncharacterized protein.	0.627
B0A54_01190	B0A54_12066	A0A4U0VIW1	A0A4U0UKP2	Uncharacterized protein.	Uncharacterized protein.	0.637
B0A54_01190	B0A54_12575	A0A4U0VIW1	A0A4U0UJF5	Uncharacterized protein.	Uncharacterized protein.	0.671
B0A54_01190	B0A54_13026	A0A4U0VIW1	A0A4U0UKL3	Uncharacterized protein.	Uncharacterized protein.	0.671
B0A54_01190	B0A54_13307	A0A4U0VIW1	A0A4U0UH51	Uncharacterized protein.	Uncharacterized protein.	0.671
B0A54_01190	B0A54_14853	A0A4U0VIW1	A0A4U0UGZ2	Uncharacterized protein.	Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.	0.744
B0A54_01190	B0A54_15705	A0A4U0VIW1	A0A4U0UA65	Uncharacterized protein.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.671
B0A54_02313	B0A54_01190	A0A4U0VBZ9	A0A4U0VIW1	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.623
B0A54_02313	B0A54_03529	A0A4U0VBZ9	A0A4U0VAE2	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.806
B0A54_02313	B0A54_08486	A0A4U0VBZ9	A0A4U0UT89	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.597
B0A54_02313	B0A54_12066	A0A4U0VBZ9	A0A4U0UKP2	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.806
B0A54_02912	B0A54_01190	A0A4U0VDE8	A0A4U0VIW1	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.671
B0A54_02912	B0A54_12575	A0A4U0VDE8	A0A4U0UJF5	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_13026	A0A4U0VDE8	A0A4U0UKL3	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_13307	A0A4U0VDE8	A0A4U0UH51	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein.	0.867
B0A54_02912	B0A54_15705	A0A4U0VDE8	A0A4U0UA65	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	Uncharacterized protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.868
B0A54_03529	B0A54_01190	A0A4U0VAE2	A0A4U0VIW1	Uncharacterized protein.	Uncharacterized protein.	0.637

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

41

average node degree:

7.45

avg. local clustering coefficient:

0.924

expected number of edges:

11

PPI enrichment p-value:

1.11e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042819

Vitamin B6 biosynthetic process

6 of 10

2.44

4.82

2.42e-10

GO:0042823

Pyridoxal phosphate biosynthetic process

5 of 6

2.59

4.39

3.76e-09

GO:0008615

Pyridoxine biosynthetic process

5 of 9

2.41

4.14

6.41e-09

GO:1901617

Organic hydroxy compound biosynthetic process

6 of 30

1.97

3.54

6.41e-09

GO:0019438

Aromatic compound biosynthetic process

7 of 258

1.1

1.17

2.47e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050570

4-hydroxythreonine-4-phosphate dehydrogenase activity

3 of 3

2.66

2.09

0.00014

GO:0050897

Cobalt ion binding

3 of 6

2.36

1.87

0.00030

GO:0000287

Magnesium ion binding

5 of 105

1.34

1.22

0.00056

GO:0051287

NAD binding

3 of 49

1.45

0.78

0.0211

GO:0046872

Metal ion binding

7 of 610

0.72

0.47

0.0174

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005622

Intracellular anatomical structure

11 of 1859

0.44

0.35

0.0027

GO:0005737

Cytoplasm

10 of 1759

0.42

0.31

0.0159

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:575

Mixed, incl. mRNA processing, and K Homology domain, type 2

5 of 5

2.66

4.4

4.56e-09

CL:7368

Pyridoxal phosphate biosynthetic process, and Glycine zipper 2TM domain

2 of 5

2.27

0.8

0.0332

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00750

Vitamin B6 metabolism

6 of 17

2.21

4.5

2.45e-10

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0664

Pyridoxine biosynthesis

3 of 6

2.36

2.01

0.00016

KW-0460

Magnesium

4 of 151

1.09

0.66

0.0192

KW-0520

NAD

3 of 74

1.27

0.66

0.0315

KW-0963

Cytoplasm

6 of 393

0.85

0.58

0.0092

KW-0560

Oxidoreductase

4 of 222

0.92

0.5

0.0406

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04166

Pyridoxal phosphate biosynthetic protein PdxA

3 of 3

2.66

2.13

0.00012

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005255

PdxA family

3 of 3

2.66

1.91

0.00031

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