| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72166.1 | KWZ75626.1 | HMPREF3198_02264 | HMPREF3198_00017 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | 0.618 |
| KWZ72166.1 | carA | HMPREF3198_02264 | HMPREF3198_02199 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: cga:Celgi_1781 6.0e-138 carbamoyl-phosphate synthase, small subunit; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the CarA family. | 0.897 |
| KWZ72166.1 | carB | HMPREF3198_02264 | HMPREF3198_02200 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.960 |
| KWZ72166.1 | pyrB | HMPREF3198_02264 | HMPREF3198_02197 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.960 |
| KWZ72166.1 | pyrC | HMPREF3198_02264 | HMPREF3198_02198 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.994 |
| KWZ72166.1 | pyrE | HMPREF3198_02264 | HMPREF3198_00193 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.995 |
| KWZ72166.1 | pyrF | HMPREF3198_02264 | HMPREF3198_02201 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.959 |
| KWZ72166.1 | pyrR | HMPREF3198_02264 | HMPREF3198_02196 | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.962 |
| KWZ75271.1 | KWZ75626.1 | HMPREF3198_00161 | HMPREF3198_00017 | Putative permease; KEGG: bcz:BCZK0244 6.8e-75 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | 0.664 |
| KWZ75626.1 | KWZ72166.1 | HMPREF3198_00017 | HMPREF3198_02264 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.618 |
| KWZ75626.1 | KWZ75271.1 | HMPREF3198_00017 | HMPREF3198_00161 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | Putative permease; KEGG: bcz:BCZK0244 6.8e-75 guanine-hypoxanthine permease; xanthine/uracil permease family protein K06901; Psort location: CytoplasmicMembrane, score: 10.00. | 0.664 |
| KWZ75626.1 | KWZ75627.1 | HMPREF3198_00017 | HMPREF3198_00018 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: mcu:HMPREF0573_10471 2.1e-80 npdA; Sir2 family NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50. | 0.472 |
| KWZ75626.1 | carA | HMPREF3198_00017 | HMPREF3198_02199 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: cga:Celgi_1781 6.0e-138 carbamoyl-phosphate synthase, small subunit; K01956 carbamoyl-phosphate synthase small subunit; Psort location: Cytoplasmic, score: 7.50; Belongs to the CarA family. | 0.695 |
| KWZ75626.1 | carB | HMPREF3198_00017 | HMPREF3198_02200 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: bcv:Bcav_2038 0. carbamoyl-phosphate synthase large subunit; K01955 carbamoyl-phosphate synthase large subunit; Belongs to the CarB family. | 0.682 |
| KWZ75626.1 | pyrB | HMPREF3198_00017 | HMPREF3198_02197 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: mcu:HMPREF0573_11715 2.1e-121 pyrB; aspartate carbamoyltransferase K00609; Psort location: Cytoplasmic, score: 9.97; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.742 |
| KWZ75626.1 | pyrC | HMPREF3198_00017 | HMPREF3198_02198 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | Putative dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.734 |
| KWZ75626.1 | pyrE | HMPREF3198_00017 | HMPREF3198_00193 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.692 |
| KWZ75626.1 | pyrF | HMPREF3198_00017 | HMPREF3198_02201 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | KEGG: iva:Isova_1604 2.0e-68 Orotidine 5'-phosphate decarboxylase K01591; Psort location: Cytoplasmic, score: 7.50; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.704 |
| KWZ75626.1 | pyrR | HMPREF3198_00017 | HMPREF3198_02196 | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | Pyrimidine operon regulatory protein/uracil phosphoribosyltransferase PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. | 0.742 |
| KWZ75627.1 | KWZ75626.1 | HMPREF3198_00018 | HMPREF3198_00017 | KEGG: mcu:HMPREF0573_10471 2.1e-80 npdA; Sir2 family NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50. | Putative permease; KEGG: hiq:CGSHiGG_01870 2.3e-49 upp; uracil phosphoribosyltransferase K02824; Psort location: CytoplasmicMembrane, score: 10.00. | 0.472 |