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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75627.1KEGG: mcu:HMPREF0573_10471 2.1e-80 npdA; Sir2 family NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50. (290 aa)    
Predicted Functional Partners:
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
    
 0.960
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.942
KWZ74941.1
Hydrolase, NUDIX family; KEGG: cai:Caci_7803 1.0e-48 NUDIX hydrolase; K03426 NAD+ diphosphatase; Psort location: Cytoplasmic, score: 7.50.
  
 
  0.933
nadK
Putative inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.928
KWZ72860.1
Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97.
  
 0.926
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.898
KWZ75196.1
KEGG: mcu:HMPREF0573_10901 6.2e-168 gdh; glutamate dehydrogenase K00262; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.895
KWZ72693.1
KEGG: mlu:Mlut_00880 4.5e-133 glutamate dehydrogenase/leucine dehydrogenase K00261; Psort location: Cytoplasmic, score: 9.97; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.895
lpdA
Dihydrolipoyl dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
  
 0.872
deoD
KEGG: ckp:ckrop_0402 6.7e-84 deoD; purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 9.67.
    
 0.862
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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