STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75240.1Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: mlu:Mlut_02710 1.3e-192 pyruvate dehydrogenase (cytochrome) K00156; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the TPP enzyme family. (574 aa)    
Predicted Functional Partners:
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.949
KWZ74990.1
NAD-dependent malic enzyme; KEGG: iva:Isova_1566 2.5e-155 malic protein NAD-binding protein; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: Cytoplasmic, score: 7.50.
  
 0.943
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.941
pyk
Pyruvate kinase; KEGG: bcv:Bcav_2215 5.6e-183 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
 0.927
KWZ74763.1
Pyruvate, phosphate dikinase; KEGG: mcu:HMPREF0573_10425 0. ppdK; pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
    
 0.920
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.911
pflB
KEGG: ahe:Arch_0430 0. formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
     
 0.909
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
 
 0.901
ilvD
Dihydroxy-acid dehydratase; KEGG: mcu:HMPREF0573_11178 3.6e-243 ilvD; dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 7.50; Belongs to the IlvD/Edd family.
 
 0.832
ald
KEGG: tbi:Tbis_0822 4.3e-121 alanine dehydrogenase; K00259 alanine dehydrogenase; Psort location: Extracellular, score: 9.60; Belongs to the AlaDH/PNT family.
     
 0.829
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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