STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75311.1Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55. (227 aa)    
Predicted Functional Partners:
KWZ75312.1
Hypothetical protein; KEGG: tel:tlr2432 0.00015 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; Psort location: CytoplasmicMembrane, score: 9.55.
       0.773
KWZ75313.1
Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 8.2e-06 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50.
       0.550
KWZ75314.1
DnaJ domain protein; KEGG: apb:SAR116_1614 1.8e-49 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67.
       0.529
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
       0.506
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
       0.506
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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