STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75312.1Hypothetical protein; KEGG: tel:tlr2432 0.00015 serine/threonine protein kinase; K08884 serine/threonine protein kinase, bacterial; Psort location: CytoplasmicMembrane, score: 9.55. (190 aa)    
Predicted Functional Partners:
KWZ75311.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.55.
       0.773
KWZ74942.1
HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.744
KWZ72634.1
ScpA/B protein; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.742
KWZ73039.1
ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mcu:HMPREF0573_10409 3.9e-111 histidine kinase K07654; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
  0.729
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  0.705
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
   
 
  0.657
KWZ75314.1
DnaJ domain protein; KEGG: apb:SAR116_1614 1.8e-49 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67.
   
   0.577
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.564
KWZ75313.1
Transcriptional regulator, MerR family; KEGG: vfi:VF_A0114 8.2e-06 methyltransferase K00599; Psort location: Cytoplasmic, score: 7.50.
       0.550
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
       0.506
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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