STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
KWZ75328.1Hsp20/alpha crystallin family protein; KEGG: apb:SAR116_0129 5.6e-09 molecular chaperone K13993; Belongs to the small heat shock protein (HSP20) family. (140 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.870
KWZ74745.1
Negative regulator of genetic competence ClpC/MecB; KEGG: mbb:BCG_3661c 0. clpC; putative ATP-dependent Clp protease ATP-binding subunit ClpC K03696; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.870
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.706
KWZ72679.1
Glutamine synthetase, beta-grasp domain protein; KEGG: bcv:Bcav_1849 3.3e-162 glutamine synthetase, type I; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.611
glnA
KEGG: ske:Sked_15370 1.6e-194 L-glutamine synthetase K01915; Psort location: Cytoplasmic, score: 9.97.
    
 
 0.611
rplP
Ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
 
 0.602
KWZ75314.1
DnaJ domain protein; KEGG: apb:SAR116_1614 1.8e-49 DnaJ family molecular chaperone K03686; Psort location: Cytoplasmic, score: 9.67.
  
 
 0.596
dnaJ
Putative chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions betwee [...]
  
 
 0.596
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
 
 0.584
KWZ75329.1
AIG2-like family protein; Psort location: Cytoplasmic, score: 7.50.
       0.505
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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