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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.970
KWZ72465.1
KEGG: cga:Celgi_2121 4.3e-41 Nucleoside-diphosphate kinase; K00940 nucleoside-diphosphate kinase; Psort location: Cytoplasmic, score: 9.97; Belongs to the NDK family.
    
 0.964
KWZ75030.1
KEGG: iva:Isova_0427 6.0e-115 DNA polymerase III, delta prime subunit; K02341 DNA polymerase III subunit delta'; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.951
KWZ75047.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 
 0.943
KWZ74398.1
LPXTG-motif protein cell wall anchor domain protein; KEGG: crd:CRES_1125 6.8e-91 nucI; 5-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
  
 
  0.915
KWZ73164.1
5'-nucleotidase protein; KEGG: ahe:Arch_0203 2.4e-111 LPXTG-motif cell wall anchor domain-containing protein; K01081 5'-nucleotidase; Psort location: Cellwall, score: 9.20; Belongs to the 5'-nucleotidase family.
 
 
  0.871
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
      0.870
KWZ75029.1
TAP-like protein; KEGG: aai:AARI_05180 6.5e-86 peptidase S33.
    
  0.846
nrdF
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
   
 
 0.783
nrdF-2
KEGG: aai:AARI_29930 8.6e-139 nrdF2; ribonucleoside-diphosphate reductase subunit beta K00526; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.783
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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