STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdInrdI protein; Probably involved in ribonucleotide reductase function. (144 aa)    
Predicted Functional Partners:
KWZ75047.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
  
 0.997
KWZ75049.1
Glutaredoxin; KEGG: apn:Asphe3_21430 3.2e-22 ribonucleoside-diphosphate reductase class Ib glutaredoxin subunit K06191.
 
  
 0.992
nrdF
Ribonucleoside-diphosphate reductase, beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
 
 0.992
nrdF-2
KEGG: aai:AARI_29930 8.6e-139 nrdF2; ribonucleoside-diphosphate reductase subunit beta K00526; Psort location: Cytoplasmic, score: 7.50.
 
 0.992
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.613
KWZ75046.1
Hypothetical protein.
       0.520
KWZ75044.1
Efflux ABC transporter, permease protein; KEGG: ase:ACPL_5256 1.4e-60 Macrolide export ATP-binding/permease protein macB K02004; Psort location: CytoplasmicMembrane, score: 10.00.
       0.517
KWZ75045.1
ABC transporter, ATP-binding protein; KEGG: ase:ACPL_5144 1.0e-64 spermidine/putrescine import ATP-binding protein potA K02003; Psort location: CytoplasmicMembrane, score: 9.51.
       0.517
nrdR
Putative transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
      
 0.459
KWZ75050.1
Hypothetical protein.
       0.440
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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