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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ75051.1S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (152 aa)    
Predicted Functional Partners:
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
 
 
 0.998
KWZ74337.1
Putative 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
    
 0.959
KWZ73911.1
Methionine synthase, vitamin-B12 independent; KEGG: teq:TEQUI_0936 5.3e-162 epoxyalkane:coenzyme M transferase; K00549 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Psort location: Cytoplasmic, score: 7.50.
    
 0.959
cysK
KEGG: cfl:Cfla_1390 2.4e-104 cysteine synthase; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.946
KWZ74770.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.0e-146 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
     
 0.914
KWZ72448.1
KEGG: bfa:Bfae_08030 2.4e-86 cystathionine beta-lyase/cystathionine gamma-synthase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.828
KWZ72290.1
KEGG: bld:BLi01290 4.8e-113 yjcJ; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.828
KWZ73007.1
ACT domain protein; KEGG: ske:Sked_09870 6.6e-29 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
     
 0.764
KWZ73008.1
Homoserine dehydrogenase; KEGG: mcu:HMPREF0573_10380 3.3e-75 hom; homoserine dehydrogenase K00003.
     
 0.764
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
 
 0.692
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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