STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
pdxSPyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (310 aa)    
Predicted Functional Partners:
KWZ74747.1
Pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2; KEGG: rdn:HMPREF0733_11098 1.7e-46 pdxT; GMP synthase (glutamine-hydrolyzing); K08681 glutamine amidotransferase.
 
 0.999
KWZ75560.1
KEGG: cva:CVAR_1324 3.3e-107 putative phosphomethylpyrimidine kinase; K00868 pyridoxine kinase; Psort location: Cytoplasmic, score: 7.50.
    
 0.931
KWZ72631.1
Transketolase; KEGG: mcu:HMPREF0573_11615 3.9e-237 tkt; transketolase K00615; Psort location: Cytoplasmic, score: 7.50; Belongs to the transketolase family.
   
 
  0.915
prs
Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 
  0.913
gap
KEGG: jde:Jden_1256 2.5e-141 glyceraldehyde-3-phosphate dehydrogenase, type I K00134; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.812
KWZ73833.1
Transaldolase; KEGG: pfr:PFREUD_19040 7.0e-121 tal2; transaldolase K00616; Psort location: Cytoplasmic, score: 7.50.
    
  0.771
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
    
  0.771
lipB
Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
      
 0.751
KWZ72458.1
Threonine synthase; KEGG: cpk:Cp1002_1475 1.9e-150 thrC; Threonine synthase; K01733 threonine synthase; Psort location: Cytoplasmic, score: 7.50.
   
    0.574
KWZ72426.1
KEGG: cfl:Cfla_1358 5.3e-68 acyl-CoA thioesterase; K10805 acyl-CoA thioesterase II.
  
  
 0.553
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.