close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metXAHomoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (441 aa)    
Predicted Functional Partners:
KWZ74770.1
O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; KEGG: jde:Jden_2111 2.0e-146 O-acetylhomoserine/O-acetylserine sulfhydrylase K01740; Psort location: Cytoplasmic, score: 9.97.
 
 0.999
KWZ73008.1
Homoserine dehydrogenase; KEGG: mcu:HMPREF0573_10380 3.3e-75 hom; homoserine dehydrogenase K00003.
 
 
 0.954
KWZ75209.1
Aspartate kinase II; KEGG: mcu:HMPREF0573_10651 5.1e-157 ask; aspartate kinase K00928; Psort location: Cytoplasmic, score: 7.50; Belongs to the aspartokinase family.
   
 0.938
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.926
cysK
KEGG: cfl:Cfla_1390 2.4e-104 cysteine synthase; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.890
KWZ72290.1
KEGG: bld:BLi01290 4.8e-113 yjcJ; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
   
 0.841
KWZ72448.1
KEGG: bfa:Bfae_08030 2.4e-86 cystathionine beta-lyase/cystathionine gamma-synthase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
   
 0.837
KWZ74177.1
Methyltransferase domain protein; KEGG: aai:AARI_10310 4.2e-43 SAM-dependent methyltransferase; Psort location: Cytoplasmic, score: 7.50.
  
  
 0.819
KWZ73007.1
ACT domain protein; KEGG: ske:Sked_09870 6.6e-29 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.793
KWZ74768.1
Hypothetical protein; KEGG: aai:AARI_16760 4.5e-46 hydrolase; Psort location: Cytoplasmic, score: 7.50.
       0.790
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.