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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folPKEGG: cms:CMS_0101 8.4e-61 dihydropteroate synthase; K00796 dihydropteroate synthase; Psort location: Cytoplasmic, score: 7.50. (278 aa)    
Predicted Functional Partners:
KWZ74785.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 0.999
KWZ72464.1
Protein FolC; KEGG: ahe:Arch_0554 3.0e-129 bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754; Psort location: Cytoplasmic, score: 7.50.
 
 0.999
folE
GTP cyclohydrolase I; KEGG: adg:Adeg_0594 1.6e-59 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
 
 0.996
pabB
Aminodeoxychorismate synthase, component I; KEGG: scy:SCATT_14640 5.7e-110 para-aminobenzoate synthase; K13950 para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.95.
 
 
 0.966
KWZ74786.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.837
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
   
 
 0.812
KWZ75620.1
Hypothetical protein; KEGG: smz:SMD_1225 2.2e-14 Aminodeoxychorismate lyase; Psort location: Cytoplasmic, score: 7.50.
  
 
 0.796
KWZ74976.1
Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase.
    
 0.741
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.674
KWZ75065.1
KEGG: xce:Xcel_0017 9.0e-57 glutamine amidotransferase of anthranilate synthase; K01664 para-aminobenzoate synthetase component II; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.643
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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