STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74785.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (420 aa)    
Predicted Functional Partners:
folP
KEGG: cms:CMS_0101 8.4e-61 dihydropteroate synthase; K00796 dihydropteroate synthase; Psort location: Cytoplasmic, score: 7.50.
  
 0.999
folE
GTP cyclohydrolase I; KEGG: adg:Adeg_0594 1.6e-59 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.998
KWZ72464.1
Protein FolC; KEGG: ahe:Arch_0554 3.0e-129 bifunctional folylpolyglutamate synthase/dihydrofolate synthase K11754; Psort location: Cytoplasmic, score: 7.50.
 
  
 0.940
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.930
pabB
Aminodeoxychorismate synthase, component I; KEGG: scy:SCATT_14640 5.7e-110 para-aminobenzoate synthase; K13950 para-aminobenzoate synthetase; Psort location: Cytoplasmic, score: 9.95.
 
  
 0.854
KWZ74786.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 10.00.
       0.830
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.774
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
  
 0.725
tilS
tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
 
  
 0.712
KWZ72753.1
Chorismate binding enzyme; KEGG: cfl:Cfla_1992 6.1e-145 anthranilate synthase component I K01657; Psort location: Cytoplasmic, score: 9.97.
 
  
 0.672
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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