STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
menCMandelate racemase/muconate lactonizing enzyme protein; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (348 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
   
 0.962
menB
Naphthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA); Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
 
   
 0.902
KWZ74800.1
O-succinylbenzoate-CoA ligase family protein; KEGG: cfi:Celf_0920 4.4e-64 AMP-dependent synthetase and ligase; K01911 O-succinylbenzoic acid--CoA ligase; Psort location: Cytoplasmic, score: 7.50.
    0.850
KWZ74803.1
Hypothetical protein; KEGG: cjk:jk1044 0.0073 5'-nucleotidase; K01081 5'-nucleotidase; Psort location: CytoplasmicMembrane, score: 9.55.
       0.773
menA
1,4-dihydroxy-2-naphthoate octaprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
 
   
 0.757
KWZ74806.1
Trypsin; KEGG: bcv:Bcav_3234 1.7e-92 2-alkenal reductase; K08372 putative serine protease PepD.
       0.637
KWZ73038.1
Hypothetical protein; KEGG: saq:Sare_4227 7.2e-06 inosine-5'-monophosphate dehydrogenase K00088.
  
     0.616
KWZ74807.1
KEGG: bcv:Bcav_3233 1.8e-67 isochorismate synthase; K02552 menaquinone-specific isochorismate synthase; Psort location: Cytoplasmic, score: 9.97.
 
   
 0.526
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
      
 0.470
KWZ74766.1
FAD linked oxidase protein; KEGG: jde:Jden_2117 1.1e-275 D-lactate dehydrogenase K06911; Psort location: CytoplasmicMembrane, score: 10.00.
  
  
 0.439
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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