node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KWZ74849.1 | ddl-2 | HMPREF3198_00491 | HMPREF3198_01772 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.658 |
KWZ74849.1 | murA | HMPREF3198_00491 | HMPREF3198_01767 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.976 |
KWZ74849.1 | murB | HMPREF3198_00491 | HMPREF3198_00472 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; Cell wall formation. | 0.692 |
KWZ74849.1 | murC | HMPREF3198_00491 | HMPREF3198_01901 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.966 |
KWZ74849.1 | murD | HMPREF3198_00491 | HMPREF3198_01898 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.824 |
KWZ74849.1 | murE | HMPREF3198_00491 | HMPREF3198_00053 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.876 |
KWZ74849.1 | murF | HMPREF3198_00491 | HMPREF3198_01896 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.735 |
KWZ74849.1 | murG | HMPREF3198_00491 | HMPREF3198_01900 | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.595 |
ddl | ddl-2 | HMPREF3198_00700 | HMPREF3198_01772 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.931 |
ddl | mraY | HMPREF3198_00700 | HMPREF3198_01897 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.718 |
ddl | murA | HMPREF3198_00700 | HMPREF3198_01767 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.659 |
ddl | murB | HMPREF3198_00700 | HMPREF3198_00472 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; Cell wall formation. | 0.797 |
ddl | murC | HMPREF3198_00700 | HMPREF3198_01901 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.988 |
ddl | murD | HMPREF3198_00700 | HMPREF3198_01898 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.787 |
ddl | murE | HMPREF3198_00700 | HMPREF3198_00053 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.729 |
ddl | murF | HMPREF3198_00700 | HMPREF3198_01896 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.996 |
ddl | murG | HMPREF3198_00700 | HMPREF3198_01900 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.912 |
ddl-2 | KWZ74849.1 | HMPREF3198_01772 | HMPREF3198_00491 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Nucleotidyl transferase; KEGG: ica:Intca_0922 2.2e-60 bifunctional glucosamine-1-phosphate acetyltransferase/UDP-N-acetylglucosamine pyrophosphorylase K04042; Psort location: Cytoplasmic, score: 9.97. | 0.658 |
ddl-2 | ddl | HMPREF3198_01772 | HMPREF3198_00700 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.931 |
ddl-2 | mraY | HMPREF3198_01772 | HMPREF3198_01897 | D-ala D-ala ligase protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.833 |