STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74892.1KEGG: ach:Achl_0534 1.3e-149 L-serine dehydratase K01752; Psort location: Cytoplasmic, score: 7.50; Belongs to the iron-sulfur dependent L-serine dehydratase family. (464 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.987
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.926
cysE
KEGG: bcv:Bcav_2610 2.4e-56 serine O-acetyltransferase K00640; Psort location: Cytoplasmic, score: 9.97.
     
 0.922
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
   
 
  0.913
KWZ74893.1
Serine transporter; KEGG: hiq:CGSHiGG_06840 0.00031 surE; stationary phase survival protein SurE K03835; Psort location: CytoplasmicMembrane, score: 10.00.
 
  
 0.889
cysK
KEGG: cfl:Cfla_1390 2.4e-104 cysteine synthase; K01738 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 
 0.849
KWZ73007.1
ACT domain protein; KEGG: ske:Sked_09870 6.6e-29 homoserine dehydrogenase; K00003 homoserine dehydrogenase; Psort location: Cytoplasmic, score: 7.50.
   
 
  0.782
KWZ73008.1
Homoserine dehydrogenase; KEGG: mcu:HMPREF0573_10380 3.3e-75 hom; homoserine dehydrogenase K00003.
   
 
  0.782
KWZ72448.1
KEGG: bfa:Bfae_08030 2.4e-86 cystathionine beta-lyase/cystathionine gamma-synthase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
     
 0.766
KWZ72290.1
KEGG: bld:BLi01290 4.8e-113 yjcJ; cystathionine beta-lyase; K01760 cystathionine beta-lyase; Psort location: Cytoplasmic, score: 9.97.
     
 0.766
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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