| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72157.1 | KWZ72583.1 | HMPREF3198_02255 | HMPREF3198_01941 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.578 |
| KWZ72157.1 | KWZ74896.1 | HMPREF3198_02255 | HMPREF3198_00539 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | 0.578 |
| KWZ72157.1 | nth | HMPREF3198_02255 | HMPREF3198_00762 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.516 |
| KWZ72157.1 | polA | HMPREF3198_02255 | HMPREF3198_02272 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.899 |
| KWZ72583.1 | KWZ72157.1 | HMPREF3198_01941 | HMPREF3198_02255 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | 0.578 |
| KWZ72583.1 | KWZ74896.1 | HMPREF3198_01941 | HMPREF3198_00539 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | 0.890 |
| KWZ72583.1 | coaE | HMPREF3198_01941 | HMPREF3198_01965 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.938 |
| KWZ72583.1 | nth | HMPREF3198_01941 | HMPREF3198_00762 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.686 |
| KWZ72583.1 | polA | HMPREF3198_01941 | HMPREF3198_02272 | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.848 |
| KWZ74896.1 | KWZ72157.1 | HMPREF3198_00539 | HMPREF3198_02255 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | 0.578 |
| KWZ74896.1 | KWZ72583.1 | HMPREF3198_00539 | HMPREF3198_01941 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.890 |
| KWZ74896.1 | coaE | HMPREF3198_00539 | HMPREF3198_01965 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.538 |
| KWZ74896.1 | mgtE | HMPREF3198_00539 | HMPREF3198_00538 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | Magnesium transporter; Acts as a magnesium transporter. | 0.560 |
| KWZ74896.1 | nth | HMPREF3198_00539 | HMPREF3198_00762 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.634 |
| KWZ74896.1 | polA | HMPREF3198_00539 | HMPREF3198_02272 | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.846 |
| coaE | KWZ72583.1 | HMPREF3198_01965 | HMPREF3198_01941 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.938 |
| coaE | KWZ74896.1 | HMPREF3198_01965 | HMPREF3198_00539 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | 0.538 |
| coaE | nth | HMPREF3198_01965 | HMPREF3198_00762 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.481 |
| coaE | polA | HMPREF3198_01965 | HMPREF3198_02272 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.703 |
| mgtE | KWZ74896.1 | HMPREF3198_00538 | HMPREF3198_00539 | Magnesium transporter; Acts as a magnesium transporter. | Formamidopyrimidine-DNA glycosylase H2TH domain protein; KEGG: mav:MAV_1708 6.3e-56 endonuclease VIII and DNA N-glycosylase with an AP lyase activity; K05522 endonuclease VIII; Belongs to the FPG family. | 0.560 |
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