STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (509 aa)    
Predicted Functional Partners:
KWZ74899.1
KEGG: bcv:Bcav_3289 7.0e-176 FAD dependent oxidoreductase; K00111 glycerol-3-phosphate dehydrogenase; Psort location: CytoplasmicMembrane, score: 8.78.
 0.997
KWZ75278.1
KEGG: kfl:Kfla_3197 4.5e-94 FAD dependent oxidoreductase; K00111 glycerol-3-phosphate dehydrogenase; Psort location: Cytoplasmic, score: 9.97.
 
 0.991
arc
Proteasome ATPase; KEGG: iva:Isova_1446 4.0e-102 proteasome ATPase K13527; Psort location: CytoplasmicMembrane, score: 8.78.
   
 0.944
KWZ74806.1
Trypsin; KEGG: bcv:Bcav_3234 1.7e-92 2-alkenal reductase; K08372 putative serine protease PepD.
   
 0.909
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
      0.732
KWZ74897.1
Acyltransferase; KEGG: xbo:XBJ1_4305 8.0e-33 acyltransferase; Psort location: Cytoplasmic, score: 7.50.
   
 
 0.683
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 
 0.651
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.589
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.587
KWZ72147.1
DNA gyrase, B subunit protein; KEGG: mcu:HMPREF0573_11792 4.1e-251 gyrB; DNA topoisomerase K02470; Psort location: Cytoplasmic, score: 9.67.
   
 
 0.587
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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