| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ72157.1 | KWZ74693.1 | HMPREF3198_02255 | HMPREF3198_00688 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.563 |
| KWZ72157.1 | KWZ74912.1 | HMPREF3198_02255 | HMPREF3198_00555 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | Hypothetical protein; KEGG: sen:SACE_1077 6.8e-75 ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 7.50. | 0.627 |
| KWZ72157.1 | KWZ74913.1 | HMPREF3198_02255 | HMPREF3198_00556 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | UvrD/REP helicase; KEGG: bcv:Bcav_2901 6.4e-150 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.67; Belongs to the helicase family. UvrD subfamily. | 0.642 |
| KWZ72157.1 | KWZ74942.1 | HMPREF3198_02255 | HMPREF3198_00586 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.762 |
| KWZ72157.1 | holA | HMPREF3198_02255 | HMPREF3198_01308 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | KEGG: bcv:Bcav_1739 1.2e-75 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.19. | 0.636 |
| KWZ72157.1 | polA | HMPREF3198_02255 | HMPREF3198_02272 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.751 |
| KWZ72157.1 | recA | HMPREF3198_02255 | HMPREF3198_01875 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.612 |
| KWZ72157.1 | topA | HMPREF3198_02255 | HMPREF3198_00330 | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.576 |
| KWZ72803.1 | KWZ74912.1 | HMPREF3198_01664 | HMPREF3198_00555 | Glycine cleavage T-protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the GcvT family. | Hypothetical protein; KEGG: sen:SACE_1077 6.8e-75 ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 7.50. | 0.597 |
| KWZ72803.1 | KWZ74913.1 | HMPREF3198_01664 | HMPREF3198_00556 | Glycine cleavage T-protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the GcvT family. | UvrD/REP helicase; KEGG: bcv:Bcav_2901 6.4e-150 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.67; Belongs to the helicase family. UvrD subfamily. | 0.517 |
| KWZ72803.1 | holA | HMPREF3198_01664 | HMPREF3198_01308 | Glycine cleavage T-protein; Psort location: Cytoplasmic, score: 7.50; Belongs to the GcvT family. | KEGG: bcv:Bcav_1739 1.2e-75 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.19. | 0.518 |
| KWZ74693.1 | KWZ72157.1 | HMPREF3198_00688 | HMPREF3198_02255 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | GIY-YIG catalytic domain protein; KEGG: bcv:Bcav_1900 1.8e-106 hypothetical protein; K02342 DNA polymerase III subunit epsilon; Psort location: Cytoplasmic, score: 9.67. | 0.563 |
| KWZ74693.1 | KWZ74912.1 | HMPREF3198_00688 | HMPREF3198_00555 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Hypothetical protein; KEGG: sen:SACE_1077 6.8e-75 ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 7.50. | 0.685 |
| KWZ74693.1 | KWZ74913.1 | HMPREF3198_00688 | HMPREF3198_00556 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD/REP helicase; KEGG: bcv:Bcav_2901 6.4e-150 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.67; Belongs to the helicase family. UvrD subfamily. | 0.722 |
| KWZ74693.1 | KWZ74942.1 | HMPREF3198_00688 | HMPREF3198_00586 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | HRDC domain protein; KEGG: xce:Xcel_0786 8.9e-192 UvrD/REP helicase; K03657 DNA helicase II / ATP-dependent DNA helicase PcrA; Psort location: Cytoplasmic, score: 9.97. | 0.980 |
| KWZ74693.1 | holA | HMPREF3198_00688 | HMPREF3198_01308 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | KEGG: bcv:Bcav_1739 1.2e-75 DNA polymerase III subunit delta; K02340 DNA polymerase III subunit delta; Psort location: Cellwall, score: 8.19. | 0.943 |
| KWZ74693.1 | polA | HMPREF3198_00688 | HMPREF3198_02272 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.989 |
| KWZ74693.1 | recA | HMPREF3198_00688 | HMPREF3198_01875 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.930 |
| KWZ74693.1 | topA | HMPREF3198_00688 | HMPREF3198_00330 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.694 |
| KWZ74911.1 | KWZ74912.1 | HMPREF3198_00554 | HMPREF3198_00555 | Hypothetical protein. | Hypothetical protein; KEGG: sen:SACE_1077 6.8e-75 ATP-dependent DNA helicase K01529; Psort location: Cytoplasmic, score: 7.50. | 0.551 |
