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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74930.1DNA-binding protein HB1; KEGG: apb:SAR116_0125 4.2e-11 histone family protein DNA-binding protein K03530; Psort location: Cytoplasmic, score: 9.97; Belongs to the bacterial histone-like protein family. (94 aa)    
Predicted Functional Partners:
cas1e
CRISPR-associated endonuclease Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
    
   0.710
dnaA
Replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family.
    
 
 0.678
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
  
 0.652
KWZ75009.1
Lsr2 family protein.
      
 0.641
KWZ74929.1
Hypothetical protein.
       0.631
cas2e
CRISPR-associated endoribonuclease Cas2; Psort location: Cytoplasmic, score: 7.50.
    
   0.606
KWZ72072.1
GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
  
 0.586
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
  
 0.569
KWZ72104.1
mIHF protein; KEGG: cmi:CMM_1780 3.1e-09 gmkA; guanylate kinase K00942; Psort location: Cytoplasmic, score: 7.50.
   
  
 0.523
KWZ74931.1
Hypothetical protein.
       0.520
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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