Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
KWZ74935.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (440 aa)    
Predicted Functional Partners:
KWZ72860.1
Isochorismatase family protein; KEGG: cfi:Celf_3076 5.6e-64 isochorismatase hydrolase; K08281 nicotinamidase/pyrazinamidase; Psort location: Cytoplasmic, score: 9.97.
 
 0.986
nadD
Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.952
KWZ75210.1
HAD hydrolase family; KEGG: mcu:HMPREF0573_10527 7.0e-89 pdxP; putative pyridoxal phosphatase K02566; Belongs to the HAD-like hydrolase superfamily.
     
  0.900
nadE
NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.774
KWZ74934.1
ATP-dependent Clp protease adaptor protein ClpS; Psort location: CytoplasmicMembrane, score: 9.55; Belongs to the ClpS family.
     
 0.676
KWZ74936.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.667
KWZ74938.1
Metallo-beta-lactamase domain protein; KEGG: rdn:HMPREF0733_11742 1.8e-35 beta-lactamase superfamily hydrolase; Psort location: Cytoplasmic, score: 7.50.
     
 0.663
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
       0.661
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.446
KWZ75627.1
KEGG: mcu:HMPREF0573_10471 2.1e-80 npdA; Sir2 family NAD-dependent deacetylase; Psort location: Cytoplasmic, score: 7.50.
 
 
 0.435
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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