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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rphtRNA nucleotidyltransferase; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (243 aa)    
Predicted Functional Partners:
KWZ74489.1
RNB-like protein; KEGG: krh:KRH_17360 3.3e-82 rnr; putative ribonuclease R; Psort location: Cytoplasmic, score: 9.97.
   
 0.999
KWZ72130.1
KEGG: bcv:Bcav_1962 4.9e-88 3'-5' exonuclease; K03684 ribonuclease D; Psort location: Cytoplasmic, score: 9.97.
   
 0.999
rdgB
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
  0.993
KWZ72173.1
KEGG: fal:FRAAL1781 3.4e-199 rpsA; 30S ribosomal protein S1 K02945; Psort location: Cytoplasmic, score: 9.97.
   
  0.984
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  0.976
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.
  
  0.966
KWZ72793.1
Hydrolase, NUDIX family; KEGG: krh:KRH_05700 4.6e-53 mutT; putative NTP pyrophosphohydrolase MutT; Psort location: Cytoplasmic, score: 7.50.
   
 0.908
hrpB
KEGG: ach:Achl_1784 3.7e-186 ATP-dependent helicase HrpB; K03579 ATP-dependent helicase HrpB; Psort location: Cytoplasmic, score: 7.50.
    
  0.893
hrpA
KEGG: ahe:Arch_0127 0. ATP-dependent helicase HrpA; K03578 ATP-dependent helicase HrpA; Psort location: Cytoplasmic, score: 7.50.
    
  0.893
guaA
GMP synthase domain protein; Catalyzes the synthesis of GMP from XMP.
  
 
 0.893
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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