| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ73149.1 | KWZ74785.1 | HMPREF3198_01507 | HMPREF3198_00422 | Hypothetical protein; KEGG: bcv:Bcav_0716 6.0e-51 pantoate/beta-alanine ligase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.500 |
| KWZ73149.1 | KWZ74954.1 | HMPREF3198_01507 | HMPREF3198_00598 | Hypothetical protein; KEGG: bcv:Bcav_0716 6.0e-51 pantoate/beta-alanine ligase. | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 0.550 |
| KWZ73149.1 | nadE | HMPREF3198_01507 | HMPREF3198_01623 | Hypothetical protein; KEGG: bcv:Bcav_0716 6.0e-51 pantoate/beta-alanine ligase. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.573 |
| KWZ74785.1 | KWZ73149.1 | HMPREF3198_00422 | HMPREF3198_01507 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Hypothetical protein; KEGG: bcv:Bcav_0716 6.0e-51 pantoate/beta-alanine ligase. | 0.500 |
| KWZ74785.1 | KWZ74954.1 | HMPREF3198_00422 | HMPREF3198_00598 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 0.580 |
| KWZ74785.1 | KWZ74957.1 | HMPREF3198_00422 | HMPREF3198_00601 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.855 |
| KWZ74785.1 | nadE | HMPREF3198_00422 | HMPREF3198_01623 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.861 |
| KWZ74785.1 | ribA | HMPREF3198_00422 | HMPREF3198_01295 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.987 |
| KWZ74954.1 | KWZ73149.1 | HMPREF3198_00598 | HMPREF3198_01507 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Hypothetical protein; KEGG: bcv:Bcav_0716 6.0e-51 pantoate/beta-alanine ligase. | 0.550 |
| KWZ74954.1 | KWZ74785.1 | HMPREF3198_00598 | HMPREF3198_00422 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.580 |
| KWZ74954.1 | KWZ74955.1 | HMPREF3198_00598 | HMPREF3198_00599 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | KEGG: gva:HMPREF0424_1199 5.6e-135 carbamoyl-phosphate synthase L chain, ATP binding domain protein; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; Psort location: Cytoplasmic, score: 7.50. | 0.999 |
| KWZ74954.1 | KWZ74956.1 | HMPREF3198_00598 | HMPREF3198_00600 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Carboxyl transferase domain protein; KEGG: bln:Blon_2285 1.0e-167 propionyl-CoA carboxylase; Psort location: Cytoplasmic, score: 7.50. | 0.998 |
| KWZ74954.1 | KWZ74957.1 | HMPREF3198_00598 | HMPREF3198_00601 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.959 |
| KWZ74954.1 | KWZ74959.1 | HMPREF3198_00598 | HMPREF3198_00603 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | BioY family protein; KEGG: apb:SAR116_1163 1.6e-27 biotin biosynthesis protein BioY K03523; Psort location: CytoplasmicMembrane, score: 10.00. | 0.858 |
| KWZ74954.1 | KWZ74960.1 | HMPREF3198_00598 | HMPREF3198_00604 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Glutathione S-transferase protein; KEGG: ssx:SACTE_5434 1.9e-31 glutathione transferase K07393; Psort location: Cytoplasmic, score: 7.50. | 0.582 |
| KWZ74954.1 | acpS | HMPREF3198_00598 | HMPREF3198_00602 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | Putative holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.837 |
| KWZ74954.1 | nadE | HMPREF3198_00598 | HMPREF3198_01623 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | NAD+ synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.731 |
| KWZ74954.1 | ribA | HMPREF3198_00598 | HMPREF3198_01295 | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the GTP cyclohydrolase II family. In the N-terminal section; belongs to the DHBP synthase family. | 0.542 |
| KWZ74955.1 | KWZ74954.1 | HMPREF3198_00599 | HMPREF3198_00598 | KEGG: gva:HMPREF0424_1199 5.6e-135 carbamoyl-phosphate synthase L chain, ATP binding domain protein; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; Psort location: Cytoplasmic, score: 7.50. | KEGG: tbi:Tbis_0702 1.1e-28 biotin/acetyl-CoA-carboxylase ligase; K03524 BirA family transcriptional regulator, biotin operon repressor / biotin-[acetyl-CoA-carboxylase] ligase; Psort location: Cytoplasmic, score: 9.97. | 0.999 |
| KWZ74955.1 | KWZ74956.1 | HMPREF3198_00599 | HMPREF3198_00600 | KEGG: gva:HMPREF0424_1199 5.6e-135 carbamoyl-phosphate synthase L chain, ATP binding domain protein; K11263 acetyl-/propionyl-CoA carboxylase, biotin carboxylase, biotin carboxyl carrier protein; Psort location: Cytoplasmic, score: 7.50. | Carboxyl transferase domain protein; KEGG: bln:Blon_2285 1.0e-167 propionyl-CoA carboxylase; Psort location: Cytoplasmic, score: 7.50. | 0.999 |