STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74978.1Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. (255 aa)    
Predicted Functional Partners:
KWZ74368.1
Aldehyde dehydrogenase family protein; KEGG: mcu:HMPREF0573_11678 0. L-proline dehydrogenase / delta-1-pyrroline-5-carboxylate dehydrogenase K13821; Psort location: Cytoplasmic, score: 9.95.
  
 
  0.965
KWZ74979.1
OsmC-like protein; Psort location: Cytoplasmic, score: 7.50.
 
     0.925
KWZ74976.1
Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase.
       0.799
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.799
KWZ74980.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.773
KWZ74981.1
Hypothetical protein; Psort location: Cytoplasmic, score: 7.50.
       0.773
KWZ72983.1
Hypothetical protein.
  
     0.640
KWZ72984.1
Hypothetical protein.
  
     0.636
KWZ72549.1
DivIVA domain protein; KEGG: tgo:TGME49_115220 4.0e-07 rhoptry protein, putative; Psort location: Cytoplasmic, score: 9.97.
  
     0.633
KWZ73873.1
Carboxylate-amine ligase, YbdK family; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
  0.622
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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