| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KWZ74957.1 | KWZ74976.1 | HMPREF3198_00601 | HMPREF3198_00621 | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | 0.473 |
| KWZ74957.1 | KWZ74979.1 | HMPREF3198_00601 | HMPREF3198_00624 | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | 0.601 |
| KWZ74957.1 | KWZ74980.1 | HMPREF3198_00601 | HMPREF3198_00625 | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.409 |
| KWZ74976.1 | KWZ74957.1 | HMPREF3198_00621 | HMPREF3198_00601 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.473 |
| KWZ74976.1 | KWZ74978.1 | HMPREF3198_00621 | HMPREF3198_00623 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | 0.799 |
| KWZ74976.1 | KWZ74979.1 | HMPREF3198_00621 | HMPREF3198_00624 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | 0.801 |
| KWZ74976.1 | KWZ74980.1 | HMPREF3198_00621 | HMPREF3198_00625 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KWZ74976.1 | KWZ74981.1 | HMPREF3198_00621 | HMPREF3198_00626 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.790 |
| KWZ74976.1 | KWZ74982.1 | HMPREF3198_00621 | HMPREF3198_00627 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mcu:HMPREF0573_10012 4.2e-107 histidine kinase; Psort location: Cytoplasmic, score: 7.50. | 0.573 |
| KWZ74976.1 | thyA | HMPREF3198_00621 | HMPREF3198_00622 | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.999 |
| KWZ74978.1 | KWZ74976.1 | HMPREF3198_00623 | HMPREF3198_00621 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | 0.799 |
| KWZ74978.1 | KWZ74979.1 | HMPREF3198_00623 | HMPREF3198_00624 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | 0.925 |
| KWZ74978.1 | KWZ74980.1 | HMPREF3198_00623 | HMPREF3198_00625 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KWZ74978.1 | KWZ74981.1 | HMPREF3198_00623 | HMPREF3198_00626 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.773 |
| KWZ74978.1 | KWZ74982.1 | HMPREF3198_00623 | HMPREF3198_00627 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: mcu:HMPREF0573_10012 4.2e-107 histidine kinase; Psort location: Cytoplasmic, score: 7.50. | 0.556 |
| KWZ74978.1 | thyA | HMPREF3198_00623 | HMPREF3198_00622 | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.799 |
| KWZ74979.1 | KWZ74957.1 | HMPREF3198_00624 | HMPREF3198_00601 | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | MaoC-like protein; KEGG: cef:CE0913 0. fasA; fatty-acid synthase I K11533; Psort location: Cytoplasmic, score: 9.95. | 0.601 |
| KWZ74979.1 | KWZ74976.1 | HMPREF3198_00624 | HMPREF3198_00621 | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | Dihydrofolate reductase; KEGG: mcu:HMPREF0573_10015 5.3e-36 putative dihydrofolate reductase; K00287 dihydrofolate reductase. | 0.801 |
| KWZ74979.1 | KWZ74978.1 | HMPREF3198_00624 | HMPREF3198_00623 | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | Signal peptide protein, YSIRK family; Psort location: CytoplasmicMembrane, score: 9.55. | 0.925 |
| KWZ74979.1 | KWZ74980.1 | HMPREF3198_00624 | HMPREF3198_00625 | OsmC-like protein; Psort location: Cytoplasmic, score: 7.50. | Hypothetical protein; Psort location: Cytoplasmic, score: 7.50. | 0.783 |