STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KWZ74990.1NAD-dependent malic enzyme; KEGG: iva:Isova_1566 2.5e-155 malic protein NAD-binding protein; K00027 malate dehydrogenase (oxaloacetate-decarboxylating); Psort location: Cytoplasmic, score: 7.50. (474 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.969
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
  
 0.961
KWZ73255.1
KEGG: xce:Xcel_0693 1.6e-107 phosphate acetyltransferase K13788; Psort location: Cytoplasmic, score: 7.50.
 
 
  
 0.959
aspA
Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.950
pyk
Pyruvate kinase; KEGG: bcv:Bcav_2215 5.6e-183 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 7.50.
  
 0.947
KWZ75240.1
Thiamine pyrophosphate enzyme, TPP binding domain protein; KEGG: mlu:Mlut_02710 1.3e-192 pyruvate dehydrogenase (cytochrome) K00156; Psort location: CytoplasmicMembrane, score: 9.51; Belongs to the TPP enzyme family.
  
 0.943
KWZ74763.1
Pyruvate, phosphate dikinase; KEGG: mcu:HMPREF0573_10425 0. ppdK; pyruvate phosphate dikinase K01006; Psort location: Cytoplasmic, score: 9.97; Belongs to the PEP-utilizing enzyme family.
   
 
 0.920
aceE
Pyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.919
pflB
KEGG: ahe:Arch_0430 0. formate acetyltransferase K00656; Psort location: Cytoplasmic, score: 9.97.
   
 
 0.908
kgd
KEGG: bcv:Bcav_1274 0. kgd; alpha-ketoglutarate decarboxylase; K00164 2-oxoglutarate dehydrogenase E1 component; Psort location: Cytoplasmic, score: 9.97.
  
 
 0.877
Your Current Organism:
Winkia neuii
NCBI taxonomy Id: 33007
Other names: ATCC 51847, Actinomyces neuii, CCUG 32252, CIP 104015, DSM 8576, W. neuii, strain 97/90
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